3-((4-fluorobenzyl)oxy)azetidine hydrochloride
3-[(4-Fluorobenzyl)oxy]azetidine
CAS: 1121620-48-1
Molecular Formula: C10H12FNO
3-((4-fluorobenzyl)oxy)azetidine hydrochloride - Names and Identifiers
3-((4-fluorobenzyl)oxy)azetidine hydrochloride - Physico-chemical Properties
| Molecular Formula | C10H12FNO |
| Molar Mass | 181.21 |
| Density | 1.15±0.1 g/cm3(Predicted) |
| Boling Point | 255.3±35.0 °C(Predicted) |
| pKa | 9.62±0.40(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11874412 |
3-((4-fluorobenzyl)oxy)azetidine hydrochloride - Introduction
3-[(4-Fluorobenzyl)oxy]azetidine is an organic compound with the chemical formula C11H13FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 75-77°C
-boiling point: unstable, volatile decomposition
-Density: 1.22g/cm³
-Soluble: Soluble in ethanol, ether and chloroform
Use:
- 3-[(4-Fluorobenzyl)oxy]azetidine is a commonly used organic synthesis intermediate, which can be used to prepare other organic compounds.
-It is also used as a functional group in drug synthesis and a modifier of drug molecules.
Preparation Method:
The synthesis of 3-[(4-Fluorobenzyl)oxy]azetidine can be achieved by the following steps:
1.4-fluorobenzyl alcohol is reacted with chloroazepine to obtain 4-fluorobenzyl chloroazepine.
2. Further, 4-fluorobenzyl chloroazepine is reacted with sodium hydroxide to generate 3-[(4-Fluorobenzyl)oxy]azetidine.
Safety Information:
- 3-[(4-Fluorobenzyl)oxy]azetidine is a chemical and must be stored properly and disposed of in accordance with relevant regulations.
-Wear appropriate personal protective equipment, such as lab gloves, goggles, and lab clothes, during operation.
-Avoid inhaling vapors, aerosols or dust to avoid respiratory or skin irritation.
-In case of contact, rinse immediately with plenty of water and seek medical attention.
-When handling or disposing, handle in accordance with local environmental regulations to avoid pollution and harm to the environment and human body.
Nature:
-Appearance: White crystalline solid
-Melting point: 75-77°C
-boiling point: unstable, volatile decomposition
-Density: 1.22g/cm³
-Soluble: Soluble in ethanol, ether and chloroform
Use:
- 3-[(4-Fluorobenzyl)oxy]azetidine is a commonly used organic synthesis intermediate, which can be used to prepare other organic compounds.
-It is also used as a functional group in drug synthesis and a modifier of drug molecules.
Preparation Method:
The synthesis of 3-[(4-Fluorobenzyl)oxy]azetidine can be achieved by the following steps:
1.4-fluorobenzyl alcohol is reacted with chloroazepine to obtain 4-fluorobenzyl chloroazepine.
2. Further, 4-fluorobenzyl chloroazepine is reacted with sodium hydroxide to generate 3-[(4-Fluorobenzyl)oxy]azetidine.
Safety Information:
- 3-[(4-Fluorobenzyl)oxy]azetidine is a chemical and must be stored properly and disposed of in accordance with relevant regulations.
-Wear appropriate personal protective equipment, such as lab gloves, goggles, and lab clothes, during operation.
-Avoid inhaling vapors, aerosols or dust to avoid respiratory or skin irritation.
-In case of contact, rinse immediately with plenty of water and seek medical attention.
-When handling or disposing, handle in accordance with local environmental regulations to avoid pollution and harm to the environment and human body.
Last Update：2024-04-09 02:00:56
