3,8''-Biapigenin
Amentoflavone
CAS: 1617-53-4;101140-06-1
Molecular Formula: C30H18O10
3,8''-Biapigenin - Names and Identifiers
| Name | Amentoflavone |
| Synonyms | NSC 295677 Biapigenin Amentoflavone AMENTOFLAVONE 3,8''-BIAPIGENIN 8,3''-Biapigenin 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-4H,4'H-[3,8'-bichroMene]-4,4'-dione 5,5′,7,7′-Tetrahydroxy-2,2′-bis(4-hydroxyphenyl)-[3,8′-bi-4H-1-benzopyran]-4,4′-dione [3,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)- 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
| CAS | 1617-53-4 101140-06-1 |
| InChI | InChI=1/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H |
3,8''-Biapigenin - Physico-chemical Properties
| Molecular Formula | C30H18O10 |
| Molar Mass | 538.46 |
| Density | 1.672±0.06 g/cm3(Predicted) |
| Melting Point | 258-260 °C |
| Boling Point | 911.7±65.0 °C(Predicted) |
| Specific Rotation(α) | 9 |
| Flash Point | 308.4°C |
| Solubility | Soluble in DMSO, soluble in methanol, ethanol, acetone, insoluble in petroleum ether. |
| Vapor Presure | 2.79E-35mmHg at 25°C |
| Appearance | Pale yellow powder |
| BRN | 1415589 |
| pKa | 5.57±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.793 |
| MDL | MFCD00017470 |
3,8''-Biapigenin - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
3,8''-Biapigenin - Reference
| Reference Show more | 1. Huang Chuanjun, Li Xiao, Hu Liangliang. Analysis of Annual Changes of Five Flavonoids in Taxus chinensis from Zhongxiang, Hubei [J]. Chinese Journal of Hospital Pharmacy, 2018, 38(17):21-24 33. 2. Wang Juandi, Ma Xiao, Song Pingshun. HPLC determination of isoquercitrin and other four flavonoids in Platycladus chinensis leaves [J]. Western Chinese Medicine, 2020,33(11):40-44. 3. Ma Fuling, Huang Dongmei, Song Shun, Wu Bin, Guo Gang, Wang Daxin, Tan Lin. Inhibitory Activity of Mountain May Tea Extract on MDA-MB-231 Proliferation of Breast Cancer Cells [J]. Journal of Tropical Crops, 2020,41(08):1693-1699. 4. [IF = 4.411] Li Yang et al."Seasonal Dynamics of Metabolites in Needles of Taxus wallichiana var. mairei." Molecules. 2016 Oct;21(10):1403 5. [IF = 3.038] Bing Cao et al."Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in Aβ 25 − 35 -Induced Mice by mTOR Signaling." Neurochem Res. 2021 Apr;46(4):921-934 6. [IF = 7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples." FOOD CHEMISTRY. 2022 Oct;390:133155 |
3,8''-Biapigenin - Introduction
Amentoflavone is a natural bioactive compound that is often extracted from the bark and buds of the spike Cedar (Sophora japonica). The following is a description of the nature, use, formulation and safety information of Amentoflavone:
Nature:
Amentoflavone is a yellow crystalline powder with a bitter taste. Its chemical structure is flavonoids, chemical formula is C21H20O11.
Use:
As Amentoflavone has a variety of biological activities, it has a wide range of applications in the pharmaceutical, food and cosmetic industries.
1. Pharmaceutical field: Amentoflavone has antibacterial, anti-inflammatory, antioxidant, desensitization and other effects, and can be used to treat inflammation, allergies, cardiovascular and cerebrovascular diseases, etc. In addition, it also has an inhibitory effect on some tumors and has potential anti-tumor application value.
2. Food field: Amentoflavone has the characteristics of enhancing the antioxidant performance and preservation effect of food, and can be used to make antioxidants, preservatives, pigments and functional foods.
3. Cosmetics field: Amentoflavone has antioxidant, whitening and anti-aging effects on the skin. It is often added to skin care products and can be used to improve skin quality and delay skin aging.
Method:
The extraction method of Amentoflavone can be water extraction, alcohol extraction, etc. Usually, the bark and flower buds of cedar are extracted through grinding, soaking, leaching, filtering and other steps, and then Amentoflavone products are obtained through crystallization, filtering, drying and other operations.
Safety Information:
Amentoflavone is generally considered safe under normal conditions of use. However, for certain groups of people, such as pregnant women, lactating women and people with allergies, should avoid prolonged or large doses. It is best to consult a doctor or professional for accurate safety information before using Amentoflavone.
Nature:
Amentoflavone is a yellow crystalline powder with a bitter taste. Its chemical structure is flavonoids, chemical formula is C21H20O11.
Use:
As Amentoflavone has a variety of biological activities, it has a wide range of applications in the pharmaceutical, food and cosmetic industries.
1. Pharmaceutical field: Amentoflavone has antibacterial, anti-inflammatory, antioxidant, desensitization and other effects, and can be used to treat inflammation, allergies, cardiovascular and cerebrovascular diseases, etc. In addition, it also has an inhibitory effect on some tumors and has potential anti-tumor application value.
2. Food field: Amentoflavone has the characteristics of enhancing the antioxidant performance and preservation effect of food, and can be used to make antioxidants, preservatives, pigments and functional foods.
3. Cosmetics field: Amentoflavone has antioxidant, whitening and anti-aging effects on the skin. It is often added to skin care products and can be used to improve skin quality and delay skin aging.
Method:
The extraction method of Amentoflavone can be water extraction, alcohol extraction, etc. Usually, the bark and flower buds of cedar are extracted through grinding, soaking, leaching, filtering and other steps, and then Amentoflavone products are obtained through crystallization, filtering, drying and other operations.
Safety Information:
Amentoflavone is generally considered safe under normal conditions of use. However, for certain groups of people, such as pregnant women, lactating women and people with allergies, should avoid prolonged or large doses. It is best to consult a doctor or professional for accurate safety information before using Amentoflavone.
Last Update：2024-04-09 21:32:38
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View History
3,8''-Biapigenin
2H-Naphtho[2,3-a]quinolizine-6,8,13(1H)-trione, 7-acetyl-3,4-dihydro- (9CI)
4-Fluoro-alpha-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene
N-{4-amino-6-[(3,5-dimethyl-1-piperidinyl)methyl]-1,3,5-triazin-2-yl}-N-(4-ethoxyphenyl)amine
(4S)-2-(((R)-2-aMino-2-(4-hydroxyphenyl)acetaMido)Methyl)-5,5-diMethylthiazolidine-4-carboxylic acid
1-(3-Chloro-2-propenyl)-4-methoxybenzene
1,3-BIS(TRIMETHYLSILOXY)-1,3-DIMETHYLDISILOXANE
1854067-58-5
BD1063(盐酸盐)
特地唑胺中间体
2H-Naphtho[2,3-a]quinolizine-6,8,13(1H)-trione, 7-acetyl-3,4-dihydro- (9CI)
4-Fluoro-alpha-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene
N-{4-amino-6-[(3,5-dimethyl-1-piperidinyl)methyl]-1,3,5-triazin-2-yl}-N-(4-ethoxyphenyl)amine
(4S)-2-(((R)-2-aMino-2-(4-hydroxyphenyl)acetaMido)Methyl)-5,5-diMethylthiazolidine-4-carboxylic acid
1-(3-Chloro-2-propenyl)-4-methoxybenzene
1,3-BIS(TRIMETHYLSILOXY)-1,3-DIMETHYLDISILOXANE
1854067-58-5
BD1063(盐酸盐)
特地唑胺中间体