3,6-Dimethoxypyridazine - Names and Identifiers
3,6-Dimethoxypyridazine - Physico-chemical Properties
Molecular Formula | C6H8N2O2
|
Molar Mass | 140.14 |
Density | 1.131±0.06 g/cm3(Predicted) |
Melting Point | 106 °C(Solv: water (7732-18-5)) |
Boling Point | 297.4±20.0 °C(Predicted) |
pKa | 2.48±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
3,6-Dimethoxypyridazine - Introduction
3,6-Dimethoxypyridazine is an organic compound with the chemical formula C6H8N2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 3,6-Dimethoxypyridazine is a white crystalline solid.
2. Melting point: Its melting point range is 78-82 degrees Celsius.
3. Solubility: 3,6-Dimethoxypyridazine is insoluble in water and is more easily soluble in organic solvents such as ethanol, dimethyl methanol, etc.
Use:
1. Pharmaceutical field: 3,6-dimethoxypyridazine can be used as an intermediate for the synthesis of antibiotics and drugs that promote plant growth.
2. Organic synthesis: It can be used for organic synthesis reactions, such as the synthesis of coumarin compounds.
Preparation Method:
3,6-Dimethoxypyridazine can be prepared by the following steps:
1. First, with acetic acid as solvent, p-nitrotoluene and ethylene glycol acetal are reacted at a certain temperature to generate m-phenylenediamine derivatives of dimethyl ethyl dione.
2. Then, the above derivative is reacted with a dimethyl oxalate, and an oxidative cyclization reaction is carried out in an alkaline medium to generate 3,6-dimethoxypyridazine.
Safety Information:
1. 3,6-Dimethoxypyridazine may irritate the eyes and skin, so you should avoid contact when using it.
2. in the operation, should prevent inhalation of its dust or spray, and ensure that there is good ventilation conditions.
3. During storage, 3,6-Dimethoxypyridazine should be kept in a dry and dark place to avoid contact with oxidizing agents.
When using 3,6-dimethoxypyridazine, be sure to follow laboratory safety procedures and strictly control the amount and concentration of use to reduce potential risks. In case of any discomfort or accident, please seek medical attention immediately and bring information about the compound.
Last Update:2024-04-09 21:01:54