3,4-dihydroxybenzamide - Names and Identifiers
Name | 3,4-dihydroxybenzamide
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Synonyms | 3,4-DIHYDROXYBENZAMIDE 3,4-dihydroxybenzamide 3,4-dihydroxy-benzamid benzamide, 3,4-dihydroxy- BENZAMIDE, 3,4-DIHYDROXY-
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CAS | 54337-90-5
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InChI | InChI=1/C7H7NO3/c8-7(11)4-1-2-5(9)6(10)3-4/h1-3,9-10H,(H2,8,11) |
3,4-dihydroxybenzamide - Physico-chemical Properties
Molecular Formula | C7H7NO3
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Molar Mass | 153.14 |
Density | 1.458±0.06 g/cm3(Predicted) |
Melting Point | 154-156°C |
Boling Point | 349.7±32.0 °C(Predicted) |
Flash Point | 165.3°C |
Vapor Presure | 2.28E-05mmHg at 25°C |
pKa | 8.48±0.18(Predicted) |
Refractive Index | 1.664 |
3,4-dihydroxybenzamide - Risk and Safety
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | 3276 |
3,4-dihydroxybenzamide - Introduction
3,4-dihydroxybenzamide is an organic compound with the chemical formula C7H7NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
3,4-dihydroxybenzamide is a solid and has the appearance of a white crystalline powder. It is soluble in water and many organic solvents such as ethanol, methanol and dichloromethane. This compound is weakly acidic and can react with a base to form a salt.
Use:
3,4-dihydroxybenzamide has many uses in the chemical industry. It can be used as dyes, catalysts and intermediates in organic synthesis. It can also be used as a reagent for protein phosphorylation studies.
Preparation Method:
3,4-dihydroxybenzamide can be prepared by reacting benzamide with heptane magnesium bromide. First, benzamide is reacted with magnesium powder in ether to form the magnesium salt of benzamide, and then with 3,4-dihydroxybenzoic acid under acidic conditions to form 3,4-dihydroxybenzamide. Finally, the product can be purified by crystallization to obtain the target product.
Safety Information:
The safety of 3,4-dihydroxybenzamide is relatively high, but some basic safety measures still need to be followed. Appropriate personal protective equipment such as glasses, gloves and protective clothing should be used during operation. Avoid inhalation or contact with the substance. If accidentally contact, should immediately rinse with plenty of water, and timely medical treatment. In addition, it should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update:2024-04-10 22:29:15