28832-07-7 - Names and Identifiers
Name | (7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
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Synonyms | Eximine L-Dicentrine L-DICENTRINE (R)-(-)-DICENTRINE Cepharanthine α-base 10,11-Dimethoxy-7-methyl-6,7,7A,8-tetrahydro-5H-benzo[G][1,3]benzodioxolo[6,5,4-de]quinoline 5H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7A,8-tetrahydro-10,11-dimethoxy-7-methyl- (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline (7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (R)-
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CAS | 28832-07-7
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InChI | InChI=1/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m1/s1 |
28832-07-7 - Physico-chemical Properties
Molecular Formula | C20H21NO4
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Molar Mass | 339.39 |
Density | 1.266±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 480.7±45.0 °C(Predicted) |
Flash Point | 142.7°C |
Vapor Presure | 2.12E-09mmHg at 25°C |
pKa | 6.65±0.20(Predicted) |
Refractive Index | 1.615 |
28832-07-7 - Introduction
(7aR)-10,11-dimethoxy-7-methyll-6, 7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline is a natural product, it belongs to the class of indole alkaloids. Its molecular formula is C19H21NO4 and its molecular weight is 327.38g/mol. (7aR)-10,11-dimethoxy-7-methyll-6, 7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5, the structure of 4-de]benzo[g]quinoline contains two rings of benzodioxane and quinoline, which has unique aromatic properties.
(7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline is a white crystal at room temperature and is soluble in ethanol, acetone and methanol. It has a strong bitter taste. The compound is stable in an acidic environment, but decomposes easily under light and alkaline conditions.
(7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5, the main use of 4-de]benzo[g]quinoline is as an active ingredient in natural medicines of alkaloids. It has antibacterial, anti-inflammatory, antioxidant and other biological activities, and is widely used in traditional Chinese medicine and herbal medicine. The bicuculline also has certain analgesic and anti-tumor activity, and has potential value for drug research and development.
(7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5, the preparation method of 4-de]benzo[g]quinoline is generally obtained by extracting it from the peony family. The extract undergoes a multi-step separation, purification and crystallization process, and finally purified (7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline.
About safety information,(7aR)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5h-[1,3]benzodioxolo[6,5, the toxicity and side effects of 4-de]benzo[g]quinoline are unknown. During use, careful protective measures are required to avoid contact with skin and eyes. For the use of any chemical substance, it is recommended to operate under the guidance of professionals and pay attention to the correct personal protective measures.
Last Update:2024-04-09 20:02:46