Name | Dihydromyricetin |
Synonyms | Ampelopsin Dihydromyricetin (+)-Dihydromyricetin Two hydrogenMyricetin DihydroMyricetin, froM Myrica rubra 3,3',4',5,5',7-hexahydroxy-flavanon Dihydromyricetin(+)-Dihydromyricetin 3,3',4',5,5',7-hexahydroxy-2,3-dihydroflavanonol (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one Ampelopsin(2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |
CAS | 27200-12-0 |
EINECS | 200-001-8 |
InChI | InChI=1/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1 |
InChIKey | KJXSIXMJHKAJOD-LSDHHAIUSA-N |
Molecular Formula | C15H12O8 |
Molar Mass | 320.25 |
Density | 1.808±0.06 g/cm3(Predicted) |
Melting Point | 239-241 °C |
Boling Point | 780.7±60.0 °C(Predicted) |
Flash Point | 296.7°C |
Solubility | Soluble in hot water, hot ethanol and acetone, soluble in ethanol, methanol, very slightly soluble in ethyl acetate, insoluble in chloroform, petroleum ether. |
Vapor Presure | 1.16E-25mmHg at 25°C |
Appearance | White or white-like powder |
Color | white to beige |
pKa | 7.38±0.60(Predicted) |
Storage Condition | -20°C |
Stability | Hygroscopic |
Refractive Index | 1.798 |
MDL | MFCD00189451 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the stems and leaves of Ampelopsis grossedentata. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29329990 |
Ampelopsis grossedentata extract:
Fujimoto tea tree is a rare and typical tea tree. It is known as dragon boat tea and longxu tea. It grows in hillside shrubs or valley woodlands at an altitude of 1300-1950 meters. It is known as the legendary health tea. Studies have shown that Ampelopsis grossedentata has anti-inflammatory and anti-cough effects, and also has a strong inhibitory effect on common bacteria in food.
Introduction of dihydromyricetin
Dihydromyricetin (DHM) is a natural extract of Ampelopsis grossedentata. For centuries, DHM has been used in Chinese medicine to treat hangovers and liquors.
Staphylococci, dihydromyricetin and other flavonoids in Ampelopsis grossedentata are the main active ingredients, and its MIC and MBC are basically the same as those of berberine, and its free radical scavenging activity is between 73.3 and 91.5. It can also reduce oxidative damage in the body, delay aging, reduce liver deformation and tissue necrosis.
How does dihydromyricetin powder work?
Apart from dihydromyricetin powder, no other product is more effective in reducing hangover symptoms. It has been extensively studied in mice and interacts with alcohol in a very unique way.
First, dihydromyricetin powder is actually able to suppress the effects of alcohol on the brain. It does this by binding to GABA receptors. GABA is a neurotransmitter affected by alcohol. After alcohol enters your bloodstream and reaches your brain, it binds to GABA receptors and enhances the effects you get from the GABA neurotransmitter. This can cause your heart rate to slow down, feel relaxed, and ultimately lead to drunkenness. Dihydromyricetin powder also binds to GABA receptors and softens the effects of alcohol on them. This can reduce acute alcohol withdrawal the next day, thereby reducing hangover symptoms.
Second, dihydromyricetin powder can enhance the liver's ability to metabolize alcohol and acetaldehyde, a toxic byproduct of alcohol. When alcohol is metabolized in the liver, it is converted to acetaldehyde. Acetaldehyde is much more toxic than alcohol and can cause extreme nausea, headaches and sensitivity to light. Dihydromyricetin powder can help your body remove acetaldehyde faster, thereby reducing the symptoms of a hangover the next day.