Fmoc-(R)-3-Amino-4-(3-methyl-phenyl)-butyric acid, also known as Fmoc-(R)-3-Amino-4-(3-methyl-phenyl)-butyric acid, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Molecular formula: C24H23NO3
-Molecular weight: 373.44g/mol
-Appearance: White crystalline powder
-Melting point: 115-119°C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and methylene chloride
Use:
Fmoc-(R)-3-Amino-4-(3-methyl-phenyl)-butyric acid is commonly used in peptide synthesis and synthesis of modified compounds in solid phase synthesis. It can be used as a protecting group to protect a specific amino group by adding an Fmoc protecting group to the amino group in order to avoid non-specific reactions during the synthesis. In addition, it can also be used as part of the structure of complex molecules in the synthesis.
Preparation Method:
The synthetic method of Fmoc-(R)-3-Amino-4-(3-methyl-phenyl)-butyric acid is complicated and usually involves multi-step reactions. One synthetic approach involves the construction of a molecular scaffold by synthesizing intermediates and performing subsequent functionalization reactions. The specific synthesis method is adjusted according to laboratory conditions and needs.
Safety Information:
At this time, no detailed toxicity studies have been conducted for Fmoc-(R)-3-Amino-4-(3-methyl-phenyl)-butyric acid. However, in general, as with any chemical, attention should be paid to common laboratory safety operations during handling and use. Wear appropriate personal protective equipment, such as laboratory gloves and goggles, to avoid direct exposure to the skin and eyes. When using, should follow the relevant safety guidelines, and avoid excessive contact and inhalation. In case of accidental contact or inhalation, seek medical help immediately.