Name | 2-Hydroxy-6-Chloroquinoxaline |
Synonyms | 6-Chloroquinoxalin-2-ol 6-chloro-2(1h)-quinoxalinon 6-CHLORO-2(1H)-QUINOXALINONE 6-chloroquinoxalin-2(1H)-one 6-Chloroquinoxaline-2(1H)-one 6-CHLORO-2-HYDROXYQUINOXALINE 2-Hydroxy-6-Chloroquinoxaline 2-HYDROXY-6-CHLOROQUINOXALINE 2(1H)-Quinoxalinone,6-chloro- 2(1H)-Quinoxalinone, 6-chloro- |
CAS | 2427-71-6 |
InChI | InChI=1/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-8(12)11-6/h1-4H,(H,11,12) |
Molecular Formula | C8H5ClN2O |
Molar Mass | 180.59 |
Density | 1.50±0.1 g/cm3(Predicted) |
Melting Point | 305 °C |
Boling Point | 160-170 °C(Press: 10 Torr) |
Flash Point | 193.6°C |
Vapor Presure | 7.46E-07mmHg at 25°C |
Appearance | Crystalline powder |
pKa | 8.10±0.70(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.688 |
Physical and Chemical Properties | This product is a white crystal, industrial light brown solid powder, difficult to dissolve in water, and alkali salt formation. |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
uses | 2-quinoxalol compounds such as 2-hydroxy-6-chloroquinoxalines are well-known intermediates in the production of medicinal chemicals and agrochemicals. 2-Hydroxy-6-chloroquinoxaline can be prepared from p-chloro-nitroacetanilide to quinoxalin-4-oxide and then reduced. 2-Hydroxy-6-chloroquinoxaline is an intermediate of the herbicide quinolone. |
production method | its preparation method is to add N-4-chloro -2-nitrophenyl acetylacetamide and solvent to the reaction kettle, heat under reduced pressure and reflux for 1.5h, cool to room temperature, transfer to the reduction kettle, add the reducing agent, the reducing agent can be sodium borohydride or sodium bisulfite, and reduce at room temperature for 1.5h, transfer to a neutralization kettle for neutralization to pH = 4, then filter, wash the filter cake to neutral, and dry to obtain the finished product. |