24044-07-3 - Names and Identifiers
Name | 2-(2-thienyl)-1,3-thiazole-4-carboxylic acid
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Synonyms | CHEMBRDG-BB 4003398 IFLAB-BB F2124-0616 2-(2-thienyl)thiazole-4-carboxylic acid 2-(Thiophen-2-yl)thiazole-4-carboxylicacid 2-thiophen-2-yl-1,3-thiazole-4-carboxylate 2-THIEN-2-YL-1,3-THIAZOLE-4-CARBOXYLIC ACID 2-(thiophen-2-yl)thiazole-4-carboxylic acid 2-(2-thienyl)-1,3-thiazole-4-carboxylic acid 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID 2-thiophen-2-yl-1,3-thiazole-4-carboxylic acid 4-Carboxy-2-(thien-2-yl)-1,3-thiazole, 2-(4-Carboxy-1,3-thiazol-2-yl)thiophene
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CAS | 24044-07-3
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InChI | InChI=1/C8H5NO2S2/c10-8(11)5-4-13-7(9-5)6-2-1-3-12-6/h1-4H,(H,10,11)/p-1 |
24044-07-3 - Physico-chemical Properties
Molecular Formula | C8H5NO2S2
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Molar Mass | 211.26 |
Density | 1.515±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 157 °C |
Boling Point | 441.5°C at 760 mmHg |
Flash Point | 220.8°C |
Vapor Presure | 1.43E-08mmHg at 25°C |
Storage Condition | 2-8°C |
24044-07-3 - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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Hazard Class | IRRITANT |
24044-07-3 - Introduction
2-(2-thienyl)-1,3-thiazole-4-carboxylic acid is an organic compound with the chemical formula C9H5NO2S2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
2-(2-thienyl)-1,3-thiazole-4-carboxylic acid is a solid with the appearance of light yellow to yellow crystals. It is insoluble in water at normal temperature, but soluble in organic solvents such as ethanol and dimethyl sulfoxide. It is a weak acid that can form the corresponding salt.
Use:
2-(2-thienyl)-1,3-thiazole-4-carboxylic acid is a commonly used organic synthesis intermediate with a wide range of applications. It can be used as a fluorescent dye, photosensitive materials, solar cell materials, organic light-emitting device materials and other raw materials. In addition, it can also be used in the field of pharmaceutical research, such as the synthesis of biologically active compounds.
Method:
2-(2-thienyl)-1,3-thiazole-4-carboxylic acid has many preparation methods. One common method is by reaction of thiazolidinone acid with bromothiophene. The specific preparation process is as follows: firstly, the thiazolyl acetic acid and the base are subjected to condensation reaction to obtain 2-(2-thienyl)-1,3-thiazol-4-one. Subsequently, 2-(2-thienyl)-1,3-thiazol-4-one is reacted with nitric acid for further oxidation to obtain the final 2-(2-thienyl)-1, 3-thiazole-4-boxylic acid.
Safety Information:
There is no clear report on the safety of 2-(2-thienyl)-1,3-thiazole-4-carboxylic acid. However, as an organic synthesis intermediate, its use still requires general laboratory safety measures. Avoid contact with skin and eyes during handling and storage, and ensure that the room is well ventilated. Seek immediate medical assistance in case of accidental exposure or inhalation.
Last Update:2024-04-09 21:54:55