Name | 3-Fluoro-4-nitroaniline |
Synonyms | Fluoronitroaniline2 Afatinib Impurity 99 3-Fluoro-4-nitroanil 3-Fluoro-4-nitroaniline 3-FLUORO-4-NITROANILINE 3-Fluoro-4-Nitro aniline 3-Fluoro-4-nitrobenzenamine 4-Amino-2-fluoronitrobenzene 3-Fluoro-4-nitro-1-benzenamine (3-fluoro-4-nitro-phenyl)amine |
CAS | 2369-13-3 |
EINECS | 219-130-6 |
InChI | InChI=1/C6H5FN2O2/c7-5-3-4(8)1-2-6(5)9(10)11/h1-3H,8H2 |
Molecular Formula | C6H5FN2O2 |
Molar Mass | 156.11 |
Density | 1.448±0.06 g/cm3(Predicted) |
Melting Point | 152-157°C |
Boling Point | 335.2±22.0 °C(Predicted) |
Flash Point | 156.6°C |
Solubility | soluble in Methanol |
Vapor Presure | 0.000121mmHg at 25°C |
Appearance | Bright brown crystal |
Color | Light yellow to Brown |
pKa | -0.02±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.603 |
MDL | MFCD03412239 |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S9 - Keep container in a well-ventilated place. |
HS Code | 29214200 |
Hazard Note | Harmful |
Hazard Class | IRRITANT |
introduction | 3-fluoro-4-nitroaniline is yellow needle-like crystal, highly toxic and easy to sublimate. Slightly soluble in cold water, soluble in boiling water, ethanol, ether, benzene and acid solution, is an important organic synthesis raw material. |
use | 3-fluoro-4-nitroaniline is aniline organic matter, which is an important chemical raw material and can be directly used to synthesize a variety of dyes and pigments. it can also synthesize pesticide clonitamine and pharmaceutical carryoma. At the same time, it is also a raw material for anti-aging agent, light stabilizer, developer and so on. |
production method | industrial production of 3-fluoro-4-nitroaniline generally uses 3-fluoro-4-nitrochlorobenzene as raw material, and can be produced by autoclave batch method with a yield of more than 98%, while continuous production by pipeline reactor has a yield of about 94%. |