23616-32-2 - Names and Identifiers
23616-32-2 - Physico-chemical Properties
Molecular Formula | C8H5ClN2
|
Molar Mass | 164.59 |
Density | 1.349±0.06 g/cm3(Predicted) |
Melting Point | 106-107℃ |
Boling Point | 307.9±22.0 °C(Predicted) |
Flash Point | 168.825°C |
Vapor Presure | 0.001mmHg at 25°C |
pKa | 2.04±0.30(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.663 |
23616-32-2 - Risk and Safety
23616-32-2 - Introduction
5-chloro-1,6-naphthyridine is an aromatic compound containing a chlorine atom. Its chemical formula is C10H6ClN, and its structure consists of a chlorine atom and a naphthyridine ring. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-chloro-1,6-naphthyridine is a white to yellowish crystalline solid.
-Solubility: It has good solubility in organic solvents, such as ethanol, methanol and dichloromethane.
-Melting point: Its melting point is about 100-102 degrees Celsius.
-The compound is relatively stable to air, light and moisture.
Use:
- 5-chloro-1,6-naphthyridine can be used as a pharmaceutical intermediate for the synthesis of various pharmaceutical compounds.
-It can also be used for electron-rich aromatization reactions in organic synthesis, such as benzene ring substitution reactions.
Method:
The synthesis of -5-chloro-1,6-naphthyridine is usually achieved by chlorination of naphthyridine compounds.
-A common preparation method is to react naphthyridine with zinc chloride or aluminum chloride under heating conditions to obtain 5-chloro-1,6-naphthyridine.
Safety Information:
- 5-chloro-1,6-naphthyridine is a chemical substance and should be handled in a safe operation method.
-Wear appropriate protective equipment such as gloves, safety glasses and laboratory coats during handling or operation.
-Avoid direct contact with skin, eyes and respiratory tract.
-This compound may be toxic to the environment, so care should be taken to avoid its discharge into the environment.
When using 5-chloro-1,6-naphthyridine, please follow the correct laboratory and safety procedures, and follow relevant regulations and guidelines. For further information, please refer to the specific chemical literature or consult a professional chemist or institution.
Last Update:2024-04-09 20:44:15