Name | 10-Gingerol |
Synonyms | 10-GINGEROL 10-Gingerol (+)-(S)-[10]-Gingerol 5-HYDROXY-1-(4-HYDROXY-3-METHOXYPHENYL)-3-TETRADECANONE (S)-12-Oxo-14-(3-methoxy-4-hydroxyphenyl)tetradecane-10-ol (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone (S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one (5S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)tetradecan-3-one (5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one |
CAS | 23513-15-7 |
InChI | InChI=1/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1 |
InChIKey | AIULWNKTYPZYAN-SFHVURJKSA-N |
Molecular Formula | C21H34O4 |
Molar Mass | 350.49 |
Density | 1.037±0.06 g/cm3(Predicted) |
Melting Point | 56-58 °C |
Boling Point | 499.7±35.0 °C(Predicted) |
Flash Point | 166℃ |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 8.35E-11mmHg at 25°C |
Appearance | white waxy |
pKa | 10.02±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.512 |
MDL | MFCD01682694 |
Physical and Chemical Properties | White waxy, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginger. |
Risk Codes | 53 - May cause long-term adverse effects in the aquatic environment |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29145019 |
Reference Show more | 1. Shi Haipei, Yan Hui, Shen Meiyu, et al. Exploration of quality control method of ginger charcoal combining HPLC fingerprint with one test and multiple evaluation method [J]. Chinese Journal of Experimental Prescritique 2020(5). 2. Liang Na Sang Ya Xin Zhou Yan Liu Weihua Li Tian Ye Wang Xianghong. HPLC-ESI-Q-TOF-MS/MS Analysis of Gingerol Compounds in Dried Ginger [J]. Food Industry Science and Technology 2018 39(09):252-256. 3. Wang Zhirong, Li Zhili, Li Mingyan, et al. Comparison of main ingredients in Fujian fresh ginger and dried ginger. 4. Wang Zhirong, Li Zhili, Li Mingyan, Gao Zidan, Wang Baohua, Li Changhong, Li Wenxu. Comparison of Main Components in Fujian Fresh Ginger and Dried Ginger [J]. Chinese patent medicine, 2020,42(08):2230-2236. 5. Shen Mei-Yu, Wang Jia-Li, Shi Hai-Pei, Yan Hui, Chen Pei-Dong, Yao Wei-Feng, Bao Bei-Hua & Zhang Li (2020) Alternative processing technology for the preparation of carbonized Zingiberis Rhizoma by stir-frying with sand, Pharmaceutical Biology, 58:1, 131-13 6. [IF = 5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway." Front Pharmacol. 2021 Jun;0:1369 7. [IF = 3.503] Shen Mei-Yu et al."Alternative processing technology for the preparation of carbonized Zingiberis Rhizoma by stir-frying with sand." Pharm Biol. 2020;58(1):131-137 |
introduction | research shows that the main active components of raw (dried) ginger are volatile oil and 10-gingerol. 10-gingerone alcohol is a general term for a variety of structurally similar substances with ginger spicy taste in raw (dried) ginger. Its structure contains 3-methoxy-4-hydroxyphenyl functional groups, mainly including gingerol (Gingerols), gingerol (Shogals), paracarinone (Paradols), ginger ketone (Zingerone), ginger diketone (Gingerdiones), ginger diketone (Gingerdiols), gingerol is its main component. |
pharmacological effects | modern pharmacological research has found that 10-gingerol is the main active ingredient of ginger's pharmacological effects and preventive and health effects, its main pharmacological effects include anti-platelet aggregation, boosting the heart, lowering blood lipids, anti-atherosclerosis, protecting gastric mucosa, preventing ulcers, protecting liver and gallbladder, analgesic, antiviral, anti-inflammatory, anticonvulsant, anti-oxidant, and anti-tumor, Anti-allergic, anti-radiation, anti-motion sickness and other pharmacological effects. Therefore, there are good reasons to expect that high-content and high-quality 10-gingerone alcohol will have a broad application field and huge market demand. |
use | 10-gingerol has been observed to have antioxidant effect on lipids and is effective in inhibiting obesity and adipose tissue inflammation. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: It has a wide range of pharmacological effects such as anti-vomiting, strengthening the heart, lowering blood pressure, lowering blood lipids, anti-platelet aggregation, anti-atherosclerosis, anti-tumor, anti-oxidation, anti-inflammatory, antipyretic and analgesic. [10]-gingerol is a bioactive compound with anti-inflammatory and antioxidant activities |
chemical properties | white wax, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginger. |