Molecular Formula | C25H34O8 |
Molar Mass | 462.53 |
Density | 1.33±0.1 g/cm3(Predicted) |
Melting Point | 170~172℃ |
Boling Point | 685.5±55.0 °C(Predicted) |
Specific Rotation(α) | [α]D20 +147~+153° (c=1, C2H5OH) (After Drying) |
Solubility | Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides. |
Appearance | neat |
Color | White to Off-White |
pKa | pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain) |
Storage Condition | −20°C |
Refractive Index | 1.587 |
In vitro study | Hydrocortisone hemisuccinate inhibits IL-6 and IL-3 bioactivity, with IC 50 s of 6.7 and 21.4 μM, respectively, and shows no cytotoxic effects on IL-6-independent MH60 cells. Hydrocortisone hemisuccinate (0.12-60 μM; 72 h) inhibits phytohemagglutinin (PHA) response in peripheral lymphocytes (PBL) and T-lymphocytes cultures. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | TU5010147 |