21594-52-5 - Names and Identifiers
Name | 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one
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Synonyms | 21594-52-5 T56 BOVM FNJ HE T56 BO DN FNJ CQ HE 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one Oxazolo[4,5-b]pyridin-2(3H)-one,6-broMo- Oxazolo[4,5-b]pyridin-2(3H)-one, 6-bromo- 6-bromo-3H-[1,3]oxazolo[4,5-b]pyridin-2-one 6-bromo[1,3]oxazolo[4,5-b]pyridin-2(3H)-one 6-broMo-2H,3H-[1,3]oxazolo[4,5-b]pyridin-2-one 6- broMo -3H- oxazole and [4,5-B] pyridine -2- ketone
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CAS | 21594-52-5
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InChI | InChI=1/C6H3BrN2O2/c7-3-1-4-5(8-2-3)9-6(10)11-4/h1-2H,(H,8,9,10) |
21594-52-5 - Physico-chemical Properties
Molecular Formula | C6H3BrN2O2
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Molar Mass | 215 |
Density | 2.19±0.1 g/cm3(Predicted) |
Melting Point | 233-235 °C |
Boling Point | 219.7±50.0 °C(Predicted) |
Appearance | Liquid |
Color | Clear colorless to amber |
pKa | 1.32±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.638 |
MDL | MFCD08689590 |
21594-52-5 - Risk and Safety
21594-52-5 - Introduction
6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one is an organic compound with the chemical formula C8H4BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one is a white or off-white crystalline solid.
2. Melting Point: about 165-169 ℃.
3. Solubility: soluble in a variety of organic solvents, such as ethanol, dichloromethane and dimethyl sulfoxide.
Use:
1. As an intermediate in organic synthesis, it can be used to synthesize other compounds.
2. As a potential bioactive molecule in drug research.
3. In scientific research, it can be used to synthesize new materials.
Method:
The preparation method of 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one is more complicated. A common preparation method is as follows:
under reflux conditions, 5-bromo -2-acetyl pyridine and nitrite are reacted, then sodium hydroxide solution and acetone are added to reflux again, and the brominated product is neutralized, after cooling and filtration, the target product is finally obtained. Note that this reaction process requires strict process control and safe operation.
Safety Information:
1. 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one needs to be stored in a dry, cool place away from direct sunlight.
2. When using should wear appropriate protective gloves and glasses, avoid contact with skin and eyes.
3. May be harmful to the environment, should avoid scattered into the soil or water.
4. When handling and disposing, the operation and disposal should be carried out in accordance with local regulations and guidelines.
Please note that the properties, uses, preparation and safety information of 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one are for informational purposes only, the specific situation needs to be studied and evaluated in detail according to the actual needs.
Last Update:2024-04-09 15:17:55