Molecular Formula | C9H6N2S3 |
Molar Mass | 238.35 |
Density | d25 1.05 (c = 0.30) |
Boling Point | >120 °C |
Flash Point | (open cup): 66°C |
Vapor Presure | 8.65E-07mmHg at 25°C |
pKa | -0.09±0.10(Predicted) |
Storage Condition | 0-6°C |
Refractive Index | 1.5500 (estimate) |
Physical and Chemical Properties | The original drug is brown-red liquid, relative density 1.38, flash point> 120.7 ℃, vapor pressure <1.33. Under normal conditions, storage is stable for 1 year, and it is easy to decompose under strong alkaline conditions. |
Risk Codes | R22 - Harmful if swallowed R26 - Very Toxic by inhalation R36/38 - Irritating to eyes and skin. R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37 - Wear suitable protective clothing and gloves. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
RTECS | XK8150900 |
HS Code | 29342000 |
Toxicity | LD50 in male, female rats (mg/kg): 752, 679 orally (Rush) |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
introduction | benzothiacene (also known as beisheng or jiasheng, English full name is 2-(thiocyanomethylthio)benzothiazole) is a broad-spectrum seed protective agent, which has significant control effect on fungal or bacterial diseases transmitted by soil and seeds. It can be used for seed dressing, soaking, root irrigation or foliar spraying, control rice blast, flax leaf spot, bacterial leaf blight, sheath blight, sugarcane pear disease, vegetable anthracnose, melon anthracnose, catchall, blight, vine cutting, citrus canker, etc. disease. The foreign market trade name is TCMTB. TCMTB is an excellent fungicide with broad spectrum, high efficiency and low toxicity. Foreign use is already large and rising rapidly. There is no domestic manufacturer, mainly because the current process technology makes the product production cost higher, it is difficult to adapt to the current domestic and foreign markets. |
application | benzothiacene (benzothiacene)(TCMTB) is a very economical and effective green fungicide. it belongs to the same type of product as the BUSAN30L of the American Buckmam company and the BIOCIDEMT30 of the French Progiven company. it can be effectively applied to seed treatment, it has a strong killing and control effect on the main bacteria, fungi and algae that exist. It has special effects for seed dressing, seed soaking and spraying to treat anthrax, rice blast, cataplexy, vertical blight and citrus ulcers. Therefore, Benzothiacene (benzothiacene) and its metabolites have large residues in plants and soil. |
Preparation | Using 2-mercaptobenzothiazole as a raw material, after chloromethylation, 2-chloromethyl thiobenzothiazole is obtained, and then according to the first The second step of the method is to further obtain benzothiazide (benzothiazide). In the chloromethylation reaction, dry benzene and 2-mercaptobenzothiazole are added to the device with a gas introduction tube in sequence, stirred at 40 ℃ to dissolve 2-mercaptobenzothiazole, paraformaldehyde is added, dry HCl gas is introduced under reflux stirring for 1~2 hours, TCL is used to track the reaction process, after the reaction, it is cooled to room temperature, and the organic layer is washed to neutral with saturated NaCl, anhydrous Na2SO4 is dried, filtered, and rotated to evaporate the solvent to obtain the crude product. The crude product is processed by silica gel G column chromatography [eluent is V (ethyl acetate): V (petroleum ether) = 2: 1] to obtain the fine compound 2-chloromethyl thiobenzothiazole. Next, according to the first synthesis method, benzothiacene (benzothiacene) can be obtained. |
toxicity | the acute oral LD50 of crude oil to rats is 2664mg/kg(1590mg/kg), the acute percutaneous LD50 of rabbits is 2000mg/kg, and the acute inhalation LC50 of rats is 0.17mg/L. Animal experiments showed no carcinogenic, teratogenic and mutagenic effects. Rainbow trout LC50 is 0.029mg/L (96h), which is low toxic to poultry. |
use | broad-spectrum seed protective agent is used for seed protection of cotton, corn, rice, wheat, sorghum, sugar beet and other crops, and can prevent and treat fungal or bacterial diseases transmitted by soil and seeds. Such as foliar spray with 30% emulsifiable concentrate 7.5mL/100 m2, spray once every 1~2 weeks, can control rice blast, bacterial blight, sheath blight and anthracnose of vegetables and melons, vertical blight. For example, 50mL of 30% emulsifiable concentrate and 100kg of cereal can be used for seed dressing to prevent and control rice seedling diseases. Used as an agricultural fungicide. |
category | pesticide |
toxicity classification | poisoning |
acute toxicity | oral-rat LD50: 1590 mg/kg |
flammability hazard characteristics | Thermal decomposition discharges toxic nitrogen oxides and sulfur oxide smoke |
storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials storage and transportation |
fire extinguishing agent | water, dry powder, dry sand, carbon dioxide, foam, 1211 fire extinguishing agent |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |