This product is for scientific research only and shall not be used for other purposes.
212650-45-8 - Introduction
4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid is an organic compound with a chemical formula of Ceph NO. The following is an introduction to its nature, use, formulation and safety information:
Use:
4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid is mainly used in organic synthesis as part of the protecting group. It can be reacted with an amine compound to form the corresponding amide compound, and the protecting group is removed by deprotection means such as acid catalysis or hydrolysis after the reaction.
Method:
4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid can be prepared by the following steps:
1. The reaction of methyl 3-morpholinecarboxylate with tert-butoxycarbonyl chloromethane (tert-butyloxycarbonyl chloromethyl ether).
2. After adding alkaline solution for reaction, 4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid is obtained.
The synthesis method needs to be carried out under an inert atmosphere, and the commonly used solvent is dichloromethane.
Safety Information:
- 4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid is a flammable liquid, contact with open flame may cause a fire.
-Need to operate in a well-ventilated place to avoid inhalation of vapors.
-Proper protective equipment such as gloves and goggles must be worn.
-Please store it properly, away from fire and oxidant, and avoid reaction with oxygen.