21203-78-1 - Names and Identifiers
21203-78-1 - Physico-chemical Properties
Molecular Formula | C5H3BrN2O2
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Molar Mass | 202.99 |
Density | 1.833±0.06 g/cm3(Predicted) |
Boling Point | 309.9±22.0 °C(Predicted) |
Flash Point | 141.2°C |
Vapor Presure | 0.00114mmHg at 25°C |
pKa | -7.03±0.12(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.614 |
21203-78-1 - Risk and Safety
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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21203-78-1 - Introduction
Pyridine, 2-bromo-6-nitro-is an organic compound with the chemical formula C5H3BrN2O2.
Nature:
Pyridine, 2-bromo-6-nitro-is a yellow crystalline solid, stable at room temperature. It is a derivative of pyridine and has pyridine-like properties. It has a melting point of 97-98 ° C. And a boiling point of 225-227 ° C. It has low solubility in water, but better solubility in organic solvents.
Use:
Pyridine, 2-bromo-6-nitro-is commonly used as a starting material or intermediate in organic synthesis. It can be used to prepare other organic compounds, such as drugs, dyes and pesticides.
Method:
Pyridine, 2-bromo-6-nitro-preparation methods are diverse, and common methods include the following:
1. Pyridine reacts with bromine in acetic acid, and then reacts with nitric acid to obtain Pyridine, 2-bromo-6-nitro-.
2. 2-amino -6-Nitro Pyridine reacts with cuprous bromide, and then reacts with acetic acid to obtain Pyridine, 2-bromo-6-nitro-.
3. Pyridine reacts with methyl bromide to generate 2-bromopyridine, which then reacts with nitric acid to obtain Pyridine, 2-bromo-6-nitro-.
Safety Information:
Pyridine, 2-bromo-6-nitro-has low toxicity, but it is still necessary to pay attention to safe operation. Avoid contact with skin, eyes and respiratory tract, and wear appropriate personal protective equipment. At the same time, it should be operated in a well-ventilated place to avoid inhaling gas or steam. In case of accidental contact, rinse immediately with plenty of water and seek medical treatment. Storage should avoid contact with oxidants, reducing agents and other substances, sealed and stored in a cool, dry place.
Last Update:2024-04-09 21:11:58