Name | Resorantel |
Synonyms | Hoe 296V 20788-07-2 Resorantel RESORANTEL Pesorantelum 4'-Bromo-g-resorcylanilide 4'-Bromo-2,6-dihydroxybenzanilide N-(4-Bomophenyl)-2,6-dihydroxybenzamide N-(4-Bromophényl)-2,6-dihydroxybenzamide N-(4-Bromophenyl)-2,6-dihydroxybenzamide benzamide, N-(4-bromophenyl)-2,6-dihydroxy- Benzamide, N-(4-bromophenyl)-2,6-dihydroxy- |
CAS | 20788-07-2 |
EINECS | 244-040-9 |
InChI | InChI=1/C13H10BrNO3/c14-8-4-6-9(7-5-8)15-13(18)12-10(16)2-1-3-11(12)17/h1-7,16-17H,(H,15,18) |
Molecular Formula | C13H10BrNO3 |
Molar Mass | 308.13 |
Density | 1.699±0.06 g/cm3(Predicted) |
Melting Point | 229-230°; mp 183-186° (LeMaire) |
Boling Point | 391.1±42.0 °C(Predicted) |
Flash Point | 190.4°C |
Vapor Presure | 1.12E-06mmHg at 25°C |
pKa | 7.62±0.35(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.728 |
In vivo study | Resorantel (65 mg/kg, a single oral dose) possesses efficacy against paramphistomiasis in naturally infected sheep. Animal Model: Five flocks of sheep in different villages of Haryana. Dosage: 65 mg/kg. Administration: A single oral dose. Result: None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis. |
biological activity | Resorantel is a safe anti-tapeworm drug for the treatment of cestodes and Thysaniezia spp. Highly effective against Paramphistomum spp. Has a certain effect. |
in vivo studies | Resorantel (65 mg/kg, a single oral dose) posses effects. Animal Model: Five flocks of sheep in different villages of Haryana. Dosage: 65 mg/kg. Administration: A single oral dose. Result: None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis. |
Animal Model: | Five flocks of sheep in different villages of Haryana. |
Dosage: | 65 mg/kg. |
Administration: | A single oral dose. |
Result: | None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis. |