3-(4-Boc-piperazin-1-yl)aniline is an organic compound with the chemical formula C16H24N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
3-(4-Boc-piperazin-1-yl)aniline is a white crystalline solid with special chemical properties. It is soluble in organic solvents such as methanol and methylene chloride at normal temperature, but insoluble in water.
Use:
The compound has important applications in the pharmaceutical field. It is a deoxyinosine diphosphatase (dUTP enzyme) inhibitor and can be used in the research and development of antiviral drugs. In addition, it can also be used as an intermediate in organic synthesis for the synthesis of other compounds.
Method:
The preparation method of 3-(4-Boc-piperazin-1-yl)aniline can be realized by the condensation reaction of piperazine and tert-butyl chloroformate. The Ester compound is first produced by the condensation reaction of tert-butyrochloroformate with piperazine under alkaline conditions. Subsequently, the ester is reduced to the target compound by a hydrogenation reaction.
Safety Information:
3-(4-Boc-piperazin-1-yl)aniline should be safe during use and storage. It is an organic compound that may cause certain health and environmental hazards. Wear appropriate personal protective equipment to avoid contact with skin and eyes during operation. At the same time, it should be operated in a well-ventilated place to avoid inhaling its vapor. In the disposal of waste to follow the appropriate rules and regulations. In case of any accident, seek medical attention immediately.