205526-31-4 - Names and Identifiers
Name | FMOC-D-3,4,5-TRIFLUOROPHENYLALANINE
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Synonyms | FMOC-D-PHE(F)3-OH FMOC-D-PHE(M,P-F3)-OH FMOC-D-PHE(3,4,5-F 3)-OH FMOC-D-PHE(3,4,5-TRIFLUORO)-OH FMOC-D-3,4,5-TRIFLUOROPHENYLALANINE Fmoc-D-3,4,5-Trifluorophenylalanine FMOC-3,4,5-TRIFLUORO-D-PHENYLALANINE D-3,4,5-TRIFLUOROPHENYLALANINE, FMOC PROTECTED 3,4,5-TRIFLUORO-D-PHENYLALANINE FMOC PROTECTED
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CAS | 205526-31-4
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InChI | InChI:1S/C24H18F3NO4/c25-19-9-13(10-20(26)22(19)27)11-21(23(29)30)28-24(31)32-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-10,18,21H,11-12H2,(H,28,31)(H,29,30) |
205526-31-4 - Physico-chemical Properties
Molecular Formula | C24H18F3NO4
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Molar Mass | 441.4 |
Storage Condition | Store at -15°C |
205526-31-4 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
205526-31-4 - Introduction
FMOC-D-3,4,5-trifluorophenylalanine is an ion-based protected amino acid with the following properties:
Nature:
-Appearance: White crystalline powder.
-molecular formula: C25H18F3NO4.
-Molecular weight: 461.41g/mol.
-Solubility: Soluble in organic solvents such as dimethyl methanol.
Use:
- FMOC-D-3, 4,5-trifluorophenylalanine is commonly used in solid-phase synthesis as the amino acid unit of the synthetic polypeptide chain.
-It can protect the amine group in amino acids during solid-phase synthesis to prevent unnecessary reactions.
-In peptide synthesis, FMOC-D-3, 4,5-trifluorophenylalanine can provide stable protection, making the synthesis process more efficient and controllable.
-It is also widely used in the field of drug development for the synthesis of biologically active peptide compounds.
Method:
- FMOC-D-3, 4,5-trifluorophenylalanine is usually prepared by chemical synthesis.
-Specifically, trifluorobenzoyl chloride is reacted with D-alanine to give FMOC-D-3, 4,5-trifluorophenylalanine.
Safety Information:
- FMOC-D-3,4,5-trifluorophenylalanine is generally a safer compound under regular conditions of use, but it is still necessary to pay attention to compliance with laboratory safety procedures.
-During operation, avoid contact with skin and eyes, and avoid inhaling its dust.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical help.
-During storage and disposal, operate in accordance with relevant safety regulations to avoid contact with combustibles and strong oxidants.
Last Update:2024-04-09 15:17:55