Name | Valinomycin |
Synonyms | Valinomycin antibioticn-329b akis(1-methylethyl)-[qr] cyclic(d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisov aleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l 1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11, 14,17,20,23,26,29,32,35-dodecone,12,24,36-trimetyl-3,6,9,15,18,21,27,30,33-non |
CAS | 2001-95-8 |
EINECS | 217-896-6 |
InChI | InChI=1/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36?,37-,38-,39-,40+,41+,42+/m0/s1 |
Molecular Formula | C54H90N6O18 |
Molar Mass | 1111.32 |
Density | 1.060 |
Melting Point | 187-190 °C |
Boling Point | 821.74°C (rough estimate) |
Specific Rotation(α) | D20 +31.0° (c = 1.6 in benzene) |
Flash Point | 87℃ |
Water Solubility | Soluble in DMSO at 10mg/ml. Insoluble in water |
Solubility | DMSO: ≥10mg/mL |
Vapor Presure | 0mmHg at 25°C |
Appearance | solid |
Color | white |
Merck | 13,9976 |
BRN | 78657 |
pKa | 11.32±0.70(Predicted) |
Storage Condition | 2-8°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Sensitive | Sensitive to light |
Refractive Index | 1.6400 (estimate) |
MDL | MFCD00005114 |
Use | Valinomycin is a fat-soluble antibiotic, a small ring peptide composed of 12 amino acids. It can selectively combine with K ions to form fat-soluble complexes, so that K can easily pass through the membrane lipid bilayer. |
Risk Codes | R27/28 - R36/37/38 - Irritating to eyes, respiratory system and skin. R21/22 - Harmful in contact with skin and if swallowed. |
Safety Description | S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S28 - After contact with skin, wash immediately with plenty of soap-suds. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 2811 6.1/PG 1 |
WGK Germany | 3 |
RTECS | YV9468000 |
FLUKA BRAND F CODES | 10-18-21 |
TSCA | Yes |
HS Code | 29419090 |
Hazard Class | 6.1(a) |
Packing Group | I |