20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol
Talatisamine
CAS: 20501-56-8
Molecular Formula: C24H39NO5
20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol - Names and Identifiers
20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol - Physico-chemical Properties
| Molecular Formula | C24H39NO5 |
| Molar Mass | 421.58 |
| Density | 1.25 |
| Melting Point | 151-152℃ |
| Boling Point | 533.9±50.0 °C(Predicted) |
| Specific Rotation(α) | 0 (c, 1.0 in EtOH) |
| Solubility | Soluble in methanol, acid water |
| Appearance | White powder or crystal |
| pKa | 13.65±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD00221750 |
20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol - Reference Information
| biological activity | talatis amine is a Aconitum alkaloid, which is a specific K channel blocker. Talatis amine attenuates the neurotoxicity of beta-amyloid oligomers on cultured cortical neurons. |
| Target | Value |
| IK channel () | 146 μM |
Last Update：2024-04-09 21:04:16
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View History
20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol
606095-28-7
269079-88-1
307552-18-7
ethyl 4-amino-2-bromobenzoate
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
sodium 2-chloro-6-[(4,6-dimethoxypyrimidin-2-yl)sulfanyl]benzoate
523981-53-5
(9H-Fluoren-9-yl)MethOxy]Carbonyl (R)-3-Amino-2-phenylpropanoic acid
Dirhodium Tetrakis[N-phthaloyl-(R)-tert-leucinate] Bis(ethyl Acetate) AdductRh2(R-PTTL)4 2EtOAc
606095-28-7
269079-88-1
307552-18-7
ethyl 4-amino-2-bromobenzoate
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
sodium 2-chloro-6-[(4,6-dimethoxypyrimidin-2-yl)sulfanyl]benzoate
523981-53-5
(9H-Fluoren-9-yl)MethOxy]Carbonyl (R)-3-Amino-2-phenylpropanoic acid
Dirhodium Tetrakis[N-phthaloyl-(R)-tert-leucinate] Bis(ethyl Acetate) AdductRh2(R-PTTL)4 2EtOAc