2-pyridinecarboxylic acid, 5-chloro-, methyl ester
5-Chloropyridine-2-carboxylic acid methyl ester
CAS: 132308-19-1
Molecular Formula: C7H6ClNO2
2-pyridinecarboxylic acid, 5-chloro-, methyl ester - Names and Identifiers
2-pyridinecarboxylic acid, 5-chloro-, methyl ester - Physico-chemical Properties
| Molecular Formula | C7H6ClNO2 |
| Molar Mass | 171.58 |
| Density | 1.294±0.06 g/cm3(Predicted) |
| Melting Point | 85-87 °C |
| Boling Point | 247.4±20.0 °C(Predicted) |
| Flash Point | 103.4°C |
| Vapor Presure | 0.0257mmHg at 25°C |
| pKa | -0.59±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.531 |
| MDL | MFCD09702466 |
2-pyridinecarboxylic acid, 5-chloro-, methyl ester - Risk and Safety
| Hazard Class | IRRITANT |
2-pyridinecarboxylic acid, 5-chloro-, methyl ester - Introduction
Methyl 5-chloropyridine-2-carboxylate, chemical formula C7H4ClNO2, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. appearance: colorless liquid.
2. Melting point:-2.3°C.
3. Boiling point: 205-206°C.
4. density: 1.35 g/cm ^ 3.
5. Solubility: Soluble in organic solvents, such as ethanol and ether.
Use:
1. 5-Chloropyridine-2-carboxylic acid methyl ester can be used as an intermediate in synthetic organic synthesis.
2. The compound can be used to synthesize organic compounds such as drugs, pesticides and azo dyes.
Preparation Method:
The preparation of methyl 5-chloropyridine-2-carboxylate usually uses the following steps:
1. Condensation reaction of 5-chloropyridine and formic acid to obtain 5-chloropyridine-2-carboxylic acid.
2. Then react with anhydrous alcohol and acid chloride to obtain the final product 5-chloropyridine -2-carboxylic acid methyl ester.
Safety Information:
1. The compound may be irritating and corrosive to the human body. Please avoid direct contact with skin and eyes.
2. When using or handling the compound, appropriate safety measures should be taken, such as wearing protective gloves and glasses.
3. Pay attention to avoid contact with combustibles during storage and use to avoid fire or explosion accidents.
4. When handling the compound, it should be carried out in a well-ventilated place to avoid poisoning or danger caused by its vapor or dust.
Nature:
1. appearance: colorless liquid.
2. Melting point:-2.3°C.
3. Boiling point: 205-206°C.
4. density: 1.35 g/cm ^ 3.
5. Solubility: Soluble in organic solvents, such as ethanol and ether.
Use:
1. 5-Chloropyridine-2-carboxylic acid methyl ester can be used as an intermediate in synthetic organic synthesis.
2. The compound can be used to synthesize organic compounds such as drugs, pesticides and azo dyes.
Preparation Method:
The preparation of methyl 5-chloropyridine-2-carboxylate usually uses the following steps:
1. Condensation reaction of 5-chloropyridine and formic acid to obtain 5-chloropyridine-2-carboxylic acid.
2. Then react with anhydrous alcohol and acid chloride to obtain the final product 5-chloropyridine -2-carboxylic acid methyl ester.
Safety Information:
1. The compound may be irritating and corrosive to the human body. Please avoid direct contact with skin and eyes.
2. When using or handling the compound, appropriate safety measures should be taken, such as wearing protective gloves and glasses.
3. Pay attention to avoid contact with combustibles during storage and use to avoid fire or explosion accidents.
4. When handling the compound, it should be carried out in a well-ventilated place to avoid poisoning or danger caused by its vapor or dust.
Last Update：2024-04-09 02:00:41
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CAS: 132308-19-1
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CAS: 132308-19-1
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View History
2-pyridinecarboxylic acid, 5-chloro-, methyl ester
p-menthane-3-carboxylic acid
Rifamycin, 4-O-[2-[(1,1-dimethylethyl)amino]-2-oxoethyl]- (9CI)
2-(哌啶-4-基)乙酸叔丁酯草酸盐
5-[(4-fluorophenoxy)methyl]-N-{2-nitro-4-methoxyphenyl}-2-furamide
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三乙基硅烷三氟甲烷磺酸酯
2-溴-5-环丁基吡啶
Isoxazole, 5-Methyl-3,4-diphenyl- (Parecoxib sodiuM inteMediate)
2-异亚丙基氨基氧乙基(R)-2-(4-(6-氯喹喔啉-2-基氧)苯氧基)丙酸酯
p-menthane-3-carboxylic acid
Rifamycin, 4-O-[2-[(1,1-dimethylethyl)amino]-2-oxoethyl]- (9CI)
2-(哌啶-4-基)乙酸叔丁酯草酸盐
5-[(4-fluorophenoxy)methyl]-N-{2-nitro-4-methoxyphenyl}-2-furamide
Carbamic acid, N-(5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester
三乙基硅烷三氟甲烷磺酸酯
2-溴-5-环丁基吡啶
Isoxazole, 5-Methyl-3,4-diphenyl- (Parecoxib sodiuM inteMediate)
2-异亚丙基氨基氧乙基(R)-2-(4-(6-氯喹喔啉-2-基氧)苯氧基)丙酸酯