2-methyl-1,3,4-oxadiazole - Names and Identifiers
Name | 2-methyl-1,3,4-oxadiazole
|
Synonyms | 2-methyl-1,3,4-oxadiazole 1,3,4-Oxadiazole, 2-methyl- 1,3,4-oxadiazole, 2-methyl-
|
CAS | 3451-51-2
|
InChI | InChI=1/C3H4N2O/c1-3-5-4-2-6-3/h2H,1H3 |
2-methyl-1,3,4-oxadiazole - Physico-chemical Properties
Molecular Formula | C3H4N2O
|
Molar Mass | 84.08 |
Density | 1.121 |
Melting Point | 180-181 °C(Solv: ethanol (64-17-5)) |
Boling Point | 123℃ |
Flash Point | 35℃ |
Vapor Presure | 16.3mmHg at 25°C |
pKa | -3.42±0.22(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.435 |
2-methyl-1,3,4-oxadiazole - Introduction
2-methyl-1,3,4-oxadiazole is an organic compound with the chemical formula C3H4N2O. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: 107-111°C
-Boiling point: no obvious boiling point
-Density: 1.21g/cm³
-Solubility: Soluble in ethanol and chloroform, slightly soluble in water, ether and petroleum ether
Use:
- 2-methyl-1,3,4-oxadiazole is often used as an intermediate in organic synthesis in chemical research, and is used to synthesize a variety of biologically active compounds.
-It can also be used as a nitrogen source for favorite reactions, participating in various reactions such as cyclization reactions, nucleophilic addition reactions, deoxy phosphorylation reactions, etc.
Preparation Method:
- 2-methyl-1,3,4-oxadiazole can be prepared by the reaction of methyl isonitrile with aldehyde or ketone.
Safety Information:
- 2-methyl-1,3,4-oxadiazole is unstable under normal conditions and should be stored in a cool, dry place, away from fire and oxidizing agents.
-Avoid inhalation, contact with skin and eyes during handling and use. If exposed, rinse immediately with plenty of water and seek medical help.
- 2-methyl-1,3,4-oxadiazole is an organic synthesis intermediate, which is only used in chemical synthesis processes in laboratory research and industry, and is not suitable for general consumer products.
Last Update:2024-04-10 22:29:15