It is an organic compound with the formula C6H3ClFNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless to light yellow liquid.
-Melting point and boiling point: Its melting point is about -16°C, and its boiling point is about 156°C.
-Solubility: Its solubility in water is low, but it can be dissolved in many organic solvents, such as ethanol, ether and dichloromethane.
-Relative density: Its relative density is about 1.38.
-Stability: It is relatively stable at room temperature, but may react when encountering light, heat, air and oxidants.
Use:
-Chemical reagent: can be used as a starting material for the synthesis of other organic compounds, such as pharmaceutical intermediates and pesticides.
-Synthetic peptide reagent: It can be used in the study of synthetic peptides and proteins, and is often used to introduce carbonyl groups and protect amino acid side chains.
-Drug research and development: It is also used in drug research and development to synthesize biologically active molecules.
Preparation Method:
The synthesis method can be obtained by the reaction of 2-fluoropyridine and formyl chloride. The specific steps are as follows:
1. A solution was prepared by dissolving 2-fluoropyridine in dichloromethane.
2. Add formyl chloride to the solution and react for a period of time.
3. The reaction product is isolated and purified by an appropriate method.
Safety Information:
-is an organic compound that should be handled in accordance with the safe practices of chemical laboratories.
-It is irritating and may cause irritation to the skin, eyes and respiratory system, so use appropriate personal protective equipment such as gloves, goggles and protective masks.
-Avoid inhalation and skin contact during operation.
-Waste and solvents should be disposed of in accordance with local regulations.