2-amino-1-(2,4-dichlorophenyl)ethan-1-ol - Names and Identifiers
2-amino-1-(2,4-dichlorophenyl)ethan-1-ol - Physico-chemical Properties
Molecular Formula | C8H9Cl2NO
|
Molar Mass | 206.07 |
Density | 1.391±0.06 g/cm3(Predicted) |
Boling Point | 354.1±37.0 °C(Predicted) |
Solubility | Methanol |
Appearance | White Power |
pKa | 11.28±0.35(Predicted) |
Storage Condition | Room Temprature |
2-amino-1-(2,4-dichlorophenyl)ethan-1-ol - Introduction
2-amino-1-(2,4-dichlorophenyl)ethan-1-ol is an organic compound with the chemical formula C8H9Cl2NO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless to slightly yellow solid.
-Solubility: Soluble in water and common organic solvents, such as ethanol, methanol and dichloromethane.
-Melting point and boiling point: Its melting point is about 85-88°C, and its boiling point is about 275°C.
Use:
-Chemical synthesis: 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol can be used as an intermediate in organic synthesis to prepare other compounds.
-Drug research: It has potential application value in the field of drug research, and may be used as a precursor for antibiotics, anti-cancer drugs or other biologically active compounds.
Preparation Method:
A common preparation method is to synthesize 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol through a substitution reaction.
The steps are as follows:
1. Reaction of 2,4-dichlorobenzaldehyde with excess ammonia in a solvent.
2. Add the reaction mixture to the sodium hydroxide solution.
3. Concentration and crystallization gave the target product: 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol.
Safety Information:
-This compound may be irritating and damaging to the eyes, skin and respiratory tract.
-Appropriate personal protective equipment, such as gloves and goggles, must be worn during handling.
-Avoid contact with oxidants and strong acids during use or storage.
-Read and follow the relevant safety data sheets and operating instructions before use.
Last Update:2024-04-09 02:00:48