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2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)-

N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine

CAS: 14611-34-8

Molecular Formula: C30H32N4O8

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  5. 2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)-

2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)- - Names and Identifiers

Name N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine
Synonyms NSC 120011
Z-Arg(Z)2-OH
Z-Arg(Z)2-Oh
Z-L-ARG(Z2)-OH
Z-ARG(DI-Z)-OH
Tris(benzyloxycarbonyl)arginine
N-ALPHA,NG,NG-TRI-CBZ-L-ARGININE
N-ALPHA,N-DELTA,N-OMEGA-TRI-Z-L-ARGININE
N-ALPHA,N-OMEGA,N-OMEGA'-TRIS-Z-L-ARGININE
Arginine, tricarboxy-, N2,N5,N5-tribenzyl ester, L-
N-ALPHA,N-OMEGA1,N-OMEGA2-TRI CARBOBENZOXY-L-ARGININE
N-ALPHA,N-DELTA,N-OMEGA-TRIBENZYLOXYCARBONYL-L-ARGININE
N-ALPHA ,N-OMEGA1,N-OMEGA2-TRI CARBOBENZOXY-L-ARGININE SODIUM SALT
Ornithine, N2,N5-dicarboxy-N5-(carboxyamidino)-, N2,N5,N5-tribenzyl ester, L-
N~2~,N~5~-bis[(benzyloxy)carbonyl]-N~5~-{N'-[(benzyloxy)carbonyl]carbamimidoyl}ornithine
N~2~,N~5~-bis[(benzyloxy)carbonyl]-N~5~-{N'-[(benzyloxy)carbonyl]carbamimidoyl}-L-ornithine
N5-(Imino(((phenylmethoxy)carbonyl)amino)methyl)-N2,N5-bis((phenylmethoxy)carbonyl)-L-ornithine
N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine
L-Ornithine, N5-(imino(((phenylmethoxy)carbonyl)amino)methyl)-N2,N5-bis((phenylmethoxy)carbonyl)-
2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)-
2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (10S)-
CAS 14611-34-8
EINECS 238-647-8
InChI InChI=1/C30H32N4O8/c31-27(33-29(38)41-20-23-13-6-2-7-14-23)34(30(39)42-21-24-15-8-3-9-16-24)18-10-17-25(26(35)36)32-28(37)40-19-22-11-4-1-5-12-22/h1-9,11-16,25H,10,17-21H2,(H,32,37)(H,35,36)(H2,31,33,38)/t25-/m0/s1

2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)- - Physico-chemical Properties

Molecular FormulaC30H32N4O8
Molar Mass576.6
Density1.27±0.1 g/cm3(Predicted)
Melting Point137-140°C
Solubility almost transparency in hot Methanol
AppearanceSolid
ColorWhite to Almost white
pKa3.94±0.21(Predicted)
Storage Condition-15°C
Refractive Index1.595
MDLMFCD00038693

2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)- - Introduction

N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine, also known as Boc-L-arginine benzyl ester, it is an organic compound. The following is a description of its nature, use, preparation and safety information:

Property: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine is a white crystalline solid, it is soluble in organic solvents such as methanol and ethanol, and has lower solubility in water. It is stable at normal temperature, but may decompose under high temperature and strong acid or alkali conditions.

Use: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine is usually used as a protecting group in chemical synthesis. It can effectively protect the amino group of arginine to prevent its participation in the reaction. This makes it very useful in the synthesis of polypeptides and proteins, where the positional selectivity of specific reactions can be controlled.

formulation: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine can be prepared by reacting the Boc Group with L-arginine. This is usually obtained by reaction of benzyloxycarbonyl chloride or tert-butylcarbonyl chloride (Boc-Cl) with L-arginine under basic conditions.

Security information: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine can be considered relatively safe under general operating conditions. However, it is an organic compound, so care should be taken to avoid direct contact with the skin, eyes or respiratory tract. In addition, it should be used in well-ventilated laboratory conditions and stored properly to prevent the risk of fire and explosion. Detailed safety operation should be evaluated according to specific experimental conditions and material safety data sheets.
Last Update:2024-04-09 20:52:54
2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)-
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View History
2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)-
巯基-三聚乙二醇-氨基
2-[(2,4-DICHLOROBENZYL)SULFANYL]-4-(4-METHOXYPHENOXY)-5-PYRIMIDINYL METHYL ETHER
2-二叔丁基膦-2′,4′,6′-三异丙基-3,6-二甲氧基-1,1′-联苯
BMS 186716-01
2-(O-TOLYLAMINO)ISONICOTINIC ACID
硫代磷酸三苯基三胺TPTA
ChloroforMate esters are G
2-DIFLUOROMETHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE
methyl 2-{[(4-chlorophenyl)methyl]sulfanyl}acetate
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