2-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenylboronic acid

2-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenylboronic acid - Names and Identifiers

Name	(2-Methyl-4-(pyrrolidin-1-ylsulfonyl)-phenyl)boronic acid
Synonyms	2-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenylboronic acid (2-Methyl-4-(pyrrolidin-1-ylsulfonyl)-phenyl)boronic acid Boronic acid, B-[2-methyl-4-(1-pyrrolidinylsulfonyl)phenyl]-
CAS	1217501-51-3

2-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C11H16BNO4S
Molar Mass	269.12
Storage Condition	2-8°C
Sensitive	IRRITANT
MDL	MFCD13195671

2-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenylboronic acid - Introduction

(2-Methyl-4-(pyrrolidin-1-ylsulfonyl)-phenyl)boronic acid is an organic compound with the chemical formula C15H21BN2O4S. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: White to off-white crystalline powder
-melting point: about 174-176 ℃
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane

Use:
This compound has important application value in organic synthesis and is often used as a ligand in metal-catalyzed reactions. In particular, in Suzuki-Miyaura coupling reactions, it can be reacted with an organic halide or sulfoxide to form the corresponding organic boronic ester. These boronic acid esters have a wide range of applications in the fields of drug synthesis and material science.

Preparation Method:
(2-Methyl-4-(pyrrolidin-1-ylsulfonyl)-phenyl)boronic acid is usually prepared by organic synthesis methods. The specific preparation method can refer to the relevant scientific literature, which cannot be expanded in detail here.

Safety Information:
This compound is relatively stable under normal operating conditions, but it is still necessary to follow safe operating procedures. It is an organic compound and may have certain sensitization and irritation, so care should be taken to avoid contact with skin and eyes when using it. At the same time, care should be taken to prevent inhalation or swallowing during operation, and to maintain good ventilation conditions. For laboratories that use the compound, relevant safety measures need to be taken, such as wearing protective gloves and glasses, and following relevant chemical handling and storage regulations.

Last Update：2024-04-09 21:11:58