Name | Catechol |
Synonyms | Catechol C.I. 76500 Pyrocatechol ai3-03995[qr] 1,2-Benzenediol 2-Hydroxyphenol benzene-1,2-diol 2-hydroxyphenol[qr] 1,2-benzenediol[qr] Benzene, o-dihydroxy- C.I. Oxidation Base 26 benzene,1,2-dihydroxy- 1,2-dihydroxybenzene[qr] 1,2-Benzenediol (pyrocatechol) |
CAS | 120-80-9 |
EINECS | 204-427-5 |
InChI | InChI=1/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H |
Molecular Formula | C6H6O2 |
Molar Mass | 110.11 |
Density | 1,371 g/cm3 |
Melting Point | 100-103 °C (lit.) |
Boling Point | 245 °C (lit.) |
Flash Point | 279°F |
Water Solubility | 430 g/L (20 ºC) |
Solubility | 430g/l |
Vapor Presure | 1 mm Hg ( 75 °C) |
Vapor Density | 3.8 (vs air) |
Appearance | Crystalline Flakes |
Color | white to faintly beige |
Exposure Limit | TLV-TWA 5 ppm (~22 mg/m3) (ACGIH). . |
Merck | 14,7999 |
BRN | 471401 |
pKa | 9.85(at 20℃) |
PH | 6 (100g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Stability | Stable. Substances to be avoided include acid chlorides, acid anhydrides, bases, oxidizing agents, nitric acid. Light sensitive; may discolour on exposure to air. Combustible. |
Sensitive | Air & Light Sensitive |
Explosive Limit | 1.97%(V) |
Refractive Index | 1.6120 (estimate) |
Physical and Chemical Properties | Character: colorless crystals. Discoloration in air and light. Its solution in the air into a tan, see light or open air discoloration, can sublimate. soluble in 2.3 times water, soluble in ethanol, ether, benzene, chloroform, soluble in pyridine and caustic liquid. |
Use | Is an important chemical intermediate, can be used as rubber hardening agent, electroplating additives, skin antiseptic, hair dye, photo developer, color photo antioxidant |
Hazard Symbols | Xn - Harmful |
Risk Codes | R21/22 - Harmful in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin. R68 - Possible risk of irreversible effects R43 - May cause sensitization by skin contact |
Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. S39 - Wear eye / face protection. |
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 2 |
RTECS | UX1050000 |
TSCA | Yes |
HS Code | 2907 29 00 |
Hazard Class | 6.1 |
Packing Group | III |
Toxicity | LD50 in mice (mg/kg): 260 orally; 190 i.p. (Lehman) |
Downstream Products | 3-Ethoxy-4-hydroxybenzaldehyde |
colorless crystals. Discoloration in air and light. The solution turned tan in air. Flammable. The relative density was 1. 37. The melting point of 1 05 deg C (104~1 05 deg C). Boiling point 246 °c (look kPa). Flash point (Open Cup) 127 °c. Can sublimate. Ignition point (in a closed kettle) 127 °c. Soluble in 2.3 times water, soluble in ethanol, ether, benzene, chloroform, soluble in pyridine and caustic liquid.
prepared by hydrolysis of O-chlorophenol in alkaline medium.
An important pharmaceutical intermediate for the preparation of berberine (berberine) and isoproterenol. Can also be prepared spices (piperonal), dyes, photosensitive materials, electroplating materials, special inks, antioxidants, light stabilizers, preservatives and accelerators.