2-Cyano-N-(2-methoxyphenyl)acetamide - Names and Identifiers
2-Cyano-N-(2-methoxyphenyl)acetamide - Physico-chemical Properties
Molecular Formula | C10H10N2O2
|
Molar Mass | 190.2 |
Density | 1.216±0.06 g/cm3(Predicted) |
Melting Point | 163-165 °C |
Boling Point | 392.0±22.0 °C(Predicted) |
Flash Point | 190.9°C |
Vapor Presure | 2.36E-06mmHg at 25°C |
pKa | -0.97±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.575 |
2-Cyano-N-(2-methoxyphenyl)acetamide - Introduction
2-Cyano-N-(2-methoxyphenyl)acetamide is an organic compound with the chemical formula C11H11N3O2.
Nature:
1. Appearance: White crystalline solid.
2. solubility: soluble in alcohol, ketone, ester and other organic solvents, insoluble in water.
3. Melting point: about 130-133°C.
4. specific gravity: about 1.28 g/mL.
Use:
1. 2-Cyano-N-(2-methoxyphenyl)acetamide can be used as a starting material and an intermediate in organic synthesis.
2. It can be used to synthesize biologically active compounds, such as antibacterial agents, antitumor drugs and anti-inflammatory agents.
Preparation Method:
2-Cyano-N-(2-methoxyphenyl)acetamide can be prepared by the following steps:
1. 2-Nitrotoluene is obtained by nitration of toluene.
2. Reduction of 2-nitrotoluene gives 2-aminotoluene.
3. Under alkaline conditions, 2-aminotoluene reacts with acetic anhydride to form 2-acetamidotoluene.
4. 2-Acetamidotoluene is reacted in the presence of sodium cyanide to give 2-Cyano-N-(2-methoxyphenyl)acetamide.
Safety Information:
1. 2-Cyano-N-(2-methoxyphenyl)acetamide has a stimulating effect on the skin, eyes and respiratory tract, and protective measures should be paid attention to when using.
2. Avoid contact with the dust or steam of the compound to avoid allergic reactions or damage.
3. It is recommended to operate in a well-ventilated place and wear protective glasses and gloves.
4. In case of contact with skin or eyes, rinse immediately with plenty of water for 15 minutes and seek medical help immediately.
Last Update:2024-04-09 15:17:59