2-Bromo-4-fluoro-6-(trifluoromethyl)aniline - Names and Identifiers
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline - Physico-chemical Properties
Molecular Formula | C7H4BrF4N
|
Molar Mass | 258.01 |
Density | 1.772g/cm3 |
Boling Point | 212.553°C at 760 mmHg |
Flash Point | 82.349°C |
Vapor Presure | 0.172mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.503 |
MDL | MFCD04973756 |
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline - Risk and Safety
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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Hazard Class | 6.1 |
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline - Introduction
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline(2-Bromo-4-fluoro-6-(trifluoromethyl)aniline) is an organic compound whose chemical formula is C7H4BrF4N.
Nature:
-Appearance: White to light yellow solid
-melting point: 63-66 ℃
-boiling point: 180-182 ℃
-Solubility: Soluble in organic solvents, such as chloroform, dichloromethane, insoluble in water.
Use:
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is an important organic synthesis intermediate, which is widely used in the fields of medicine, pesticide, dye and functional materials.
Preparation Method:
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline has many preparation methods, and can usually be synthesized in the following ways:
1. taking 2-amino -5-fluoro trifluorotoluene as raw material and bromination reaction to obtain the compound;
2. taking 2-bromo-5-fluorobenzotrifluoride as raw material, and obtaining the compound by amination reaction;
3. Taking 2-amino-3-bromo-5-fluorotoluene as raw material, the compound was obtained by fluorination reaction.
Safety Information:
- 2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is less toxic, but as an organic compound, it should follow safe operating procedures.
-Wear chemical protective goggles, protective gloves and protective mask during operation.
-avoid contact with the skin, such as accidental contact, should immediately rinse with plenty of water.
-Avoid inhaling its dust or vapor and ensure that the experimental site is well ventilated.
-When storing, store the compound in a dry, well-ventilated place away from fire and oxidizing agents.
Last Update:2024-04-09 20:15:17