2-Bromo-3,4-Difluoroaniline - Names and Identifiers
2-Bromo-3,4-Difluoroaniline - Physico-chemical Properties
Molecular Formula | C6H4BrF2N
|
Molar Mass | 208 |
Density | 1.788±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 236.4±35.0℃ (760 Torr) |
Flash Point | 96.8±25.9℃ |
Appearance | Solid |
pKa | 1.58±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
MDL | MFCD11035924 |
2-Bromo-3,4-Difluoroaniline - Risk and Safety
2-Bromo-3,4-Difluoroaniline - Introduction
2-Bromo-3, 4-difluoroaniline is an organic compound with the chemical formula C6H4BrF2N. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to slightly yellow crystal or crystalline powder
-Solubility: Soluble in organic solvents such as alcohols, ketones and ethers, insoluble in water
-Melting point: about 60-62 degrees Celsius
-Stability: Stable at room temperature, can be used as an organic synthesis reagent
Use:
-2-Bromo-3, 4-difluoroaniline can be used as an intermediate in drug synthesis, and can also be used as a catalyst and reagent in organic synthesis reactions
-It is also used as a precursor for organic light-emitting diode (OLED) materials, used to make displays and lighting equipment
-In the field of dyes, it can be used as one of the building blocks of dye molecules
Preparation Method:
2-Bromo-3, 4-difluoroaniline can be prepared by the following methods:
1. in the bottom of the reaction, 2-bromoaniline and 3,4-difluoronitrobenzene reaction.
2. First prepare 2-bromo-1-amino-3, 4-difluorobenzene, then react with alkali, and then acidify to obtain 2-bromo-3, 4-difluoroaniline.
Safety Information:
-2-Bromo-3, 4-difluoroaniline is less toxic, but should still follow the basic safe handling of chemicals, such as wearing protective gloves, glasses and respirators.
-Avoid contact with skin and eyes. For example, rinse immediately with plenty of water and seek medical advice.
-Avoid contact with oxidants and strong acids during storage and use.
-The compound should be stored in a closed container, avoiding contact with air.
Last Update:2024-04-09 02:00:41