Name | 2-Amino-6-chloropurine |
Synonyms | AURORA KA-689 6-Chloroguanine 6-CHLOROGUANINE Clofarabine Impurity 3 2-AMINO-6-CHLOROPURINE 6-CHLORO-2-AMINOPURINE 2-Amino-6-chloropurine 2-amino-6-chloro-purin 2-Amino-6-chloro-purine 6-chloro-7H-purin-2-amine 6-chloro-5H-purin-2-amine 6-chloroguanine crystalline 6-Chloro-7H-purin-2-ylamine 6-chloro-7H-purin-2-ylamine 6-CHLORO-9H-PURIN-2-YLAMINE |
CAS | 10310-21-1 |
EINECS | 233-686-7 |
InChI | InChI=1/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11) |
InChIKey | RYYIULNRIVUMTQ-UHFFFAOYSA-N |
Molecular Formula | C5H4ClN5 |
Molar Mass | 169.57 |
Density | 1.4937 (rough estimate) |
Melting Point | >300 °C (lit.) |
Boling Point | 279.76°C (rough estimate) |
Flash Point | 331.1°C |
Water Solubility | 1.7 g/L (20 ºC) |
Solubility | Solubility in 1mol/L NaOH; very faint turbidity. |
Vapor Presure | 1.75E-15mmHg at 25°C |
Appearance | White to yellow crystalline powder |
Color | White to yellow |
BRN | 9626 |
pKa | 6.65±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.6110 (estimate) |
MDL | MFCD00075252 |
Physical and Chemical Properties | Melting point 300°C water-soluble 1.7g/L (20°C) |
Use | Used as an intermediate of acyclovir |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
RTECS | UO7502000 |
FLUKA BRAND F CODES | 10 |
HS Code | 29339900 |
Hazard Note | Irritant/Keep Cold |
Hazard Class | IRRITANT, KEEP COLD |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
uses | intermediates of antiviral agents famciclovir and panciclovir. Used as an intermediate for acyclovir |
Production method | It can be made from 2,9-diacylguanine or 2,4, 5-triamino-6-chloropyrimidine. |