2-(trifluoromethoxy)benzylamine - Names and Identifiers
2-(trifluoromethoxy)benzylamine - Physico-chemical Properties
Molecular Formula | C8H8F3NO
|
Molar Mass | 191.15 |
Density | 1.275±0.06 g/cm3(Predicted) |
Boling Point | 77°C 12mm |
Flash Point | 77°C/12mm |
Vapor Presure | 0.946mmHg at 25°C |
BRN | 9257237 |
pKa | 8.37±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Sensitive | Air Sensitive |
Refractive Index | 1.4531 |
MDL | MFCD00085176 |
2-(trifluoromethoxy)benzylamine - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
R43 - May cause sensitization by skin contact
R36 - Irritating to the eyes
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S36/37 - Wear suitable protective clothing and gloves.
|
UN IDs | UN2735 |
Hazard Note | Corrosive |
Hazard Class | 8 |
Packing Group | III |
2-(trifluoromethoxy)benzylamine - Introduction
2-(trifluoromethoxy)benzylamine, also known as 2-(Trifluoromethoxy) benzylamine, has the chemical formula C8H8F3NO. It is an organic compound with the following properties:
Physical Properties:
Appearance: Colorless liquid or solid
Density: approx. 1.25g/cm³
Melting point: About -20 ℃
Boiling point: About 177-178 ℃
Solubility: Soluble in common organic solvents, such as ethanol, chloroform, etc.
Chemical Properties:
2-(trifluoromethoxy)benzylamine is a compound containing trifluoromethoxy and benzylamine. Its special structure gives it some unique properties. It can be used as a driving group of trifluoromethoxy in some organic reactions, and can participate in nucleophilic substitution reactions, substitution reactions, coupling reactions and other chemical reactions.
Application areas:
2-(trifluoromethoxy)benzylamine has a wide range of applications in organic synthesis. It can be used in the synthesis of intermediates, such as oxalates, ketones, amides, etc. In addition, it can also be used in drug synthesis, Pesticide Synthesis, dye synthesis and other fields.
Preparation Method:
2-(trifluoromethoxy)benzylamine can be prepared by a variety of methods. Commonly used methods include a condensation reaction using trifluoromethyl ether and benzylamine under basic conditions, and a reaction using trifluoromethyl alcohol and benzylamine in the presence of an active hydrogen compound can also be carried out.
Safety Information:
When operating 2-(trifluoromethoxy)benzylamine, personal protective measures should be taken, such as wearing protective glasses, protective gloves and protective clothing, avoiding contact with skin and inhalation of vapors. During storage, the container should be kept sealed and stored in a dry, cool and ventilated place.
Last Update:2024-04-09 02:00:43