2-(Methylamino)ethylamine hydrochloride, N1-BOC protected, N-(tert-Butoxycarbonyl)-2-(methylamino)ethylamine hydrochloride - Names and Identifiers
2-(Methylamino)ethylamine hydrochloride, N1-BOC protected, N-(tert-Butoxycarbonyl)-2-(methylamino)ethylamine hydrochloride - Physico-chemical Properties
Molecular Formula | C8H19ClN2O2
|
Molar Mass | 210.7 |
Melting Point | 129-130°C |
Boling Point | 296.4°C at 760 mmHg |
Flash Point | 133.1°C |
Vapor Presure | 0.00108mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
MDL | MFCD06796281 |
Use | This product is for scientific research only and shall not be used for other purposes. |
2-(Methylamino)ethylamine hydrochloride, N1-BOC protected, N-(tert-Butoxycarbonyl)-2-(methylamino)ethylamine hydrochloride - Risk and Safety
Risk Codes | 25 - Toxic if swallowed
|
Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
HS Code | 29214990 |
Hazard Note | Irritant |
2-(Methylamino)ethylamine hydrochloride, N1-BOC protected, N-(tert-Butoxycarbonyl)-2-(methylamino)ethylamine hydrochloride - Introduction
tert-butyl [2-(methylamino)ethyl]carbamate hydrochloride is an organic compound with the chemical formula C7H15NO2.HCl. The following is a description of the properties, uses, preparation and safety information of the compound:
1. Nature:
-Appearance: White crystalline solid.
-Melting point: About 186-189 ° C.
-Solubility: Soluble in some organic solvents (such as methanol, dimethylformamide and ethyl acetate).
2. Use:
tert-butyl [2-(methylamino)ethyl]carbamate hydrochloride is a commonly used organic synthesis intermediate. It can be present in the amino compound as a protecting group (Boc protecting group) for protecting other functional groups in the amino reaction process from being unnecessarily affected. In the synthesis of drugs, ligands and other complex organic molecules, Boc protecting groups are often used to improve the efficiency and selectivity of the synthesis.
3. Preparation method:
The preparation of tert-butyl [2-(methylamino)ethyl]carbamate hydrochloride can be carried out by the following steps:
-First, 2-methylaminoethylamine is reacted with tert-butoxycarbonylating agent to produce N-BOC-2-methylaminoethylamine.
-Then, react N-BOC-2-methylaminoethylamine with hydrochloric acid to generate tert-butyl [2-(methylamino)ethyl]carbamate hydrochloride.
4. Safety Information:
- tert-butyl [2-(methylamino)ethyl]carbamate hydrochloride should be used and handled under appropriate protective measures, such as wearing appropriate protective glasses, gloves and laboratory clothing.
-Avoid inhalation, ingestion and contact with skin, and try to avoid dust and aerosols.
-Store in a closed container, away from fire and oxidizing agents. Avoid contact with organic halogens, acids and oxidants.
-If accidental exposure or adverse reactions occur, please seek the assistance of a doctor and deal with it according to the relevant safety data sheet.
Please note that the information provided above is for reference only. Please follow the experimental procedures and safe operating instructions when using this compound.
Last Update:2024-04-09 21:01:54