2-(3-溴-4-甲氧基苯基)乙酸

2-(3-溴-4-甲氧基苯基)乙酸 - Names and Identifiers

Name	3-Bromo-4-methoxyphenylaceticacid
Synonyms	RARECHEM AL BO 0336 3-Bromo-4-methoxyphenylaceticacid (3-Bromo-4-methoxyphenyl)aceticAci 3-BROMO-4-METHOXYPHENYLACETIC ACID 3-Bromo-4-methoxyphenylacetic acid Benzeneacetic acid, 3-bromo-4-methoxy- 2-(3-bromo-4-methoxyphenyl)acetic acid 2-(3-bromo-4-methoxy-phenyl)acetic acid Benzeneacetic acid,3- bromo-4-methoxy- 2-(3-bromo-4-methoxy-phenyl)ethanoic acid
CAS	774-81-2
InChI	InChI=1/C9H9BrO3/c1-13-8-3-2-6(4-7(8)10)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)

2-(3-溴-4-甲氧基苯基)乙酸 - Physico-chemical Properties

Molecular Formula	C9H9BrO3
Molar Mass	245.07
Density	1.560±0.06 g/cm3(Predicted)
Melting Point	115-117°C
Boling Point	361.1±27.0 °C(Predicted)
Flash Point	172.2°C
Solubility	soluble in Methanol
Vapor Presure	7.62E-06mmHg at 25°C
Appearance	Solid
Color	White to Light yellow
pKa	4.27±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.572
MDL	MFCD00017538

2-(3-溴-4-甲氧基苯基)乙酸 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 3077 9/PG III
Hazard Class	IRRITANT
Packing Group	III

2-(3-溴-4-甲氧基苯基)乙酸 - Introduction

It is an organic compound with the chemical formula C9H9BrO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystal or crystalline powder
-Melting Point: 144-147°C
-Boiling Point: 330-332°C
-Soluble: Soluble in ethanol, ether and dichloromethane, insoluble in water
-Molecular weight: 249.07g/mol

Use:
-It can be used as an intermediate in organic synthesis and is commonly used in the synthesis of many drugs and pesticides.
-It can also be used to prepare biologically active compounds, such as anti-inflammatory drugs, antibiotics, etc.

Preparation Method:
There are many preparation methods, but the following is a commonly used method:
1. The methyl position of phenylacetic acid is protected, usually using methanol and sulfuric acid as reactants to generate methyl phenylacetate (methoxyphenylacetic acid).
2. The bromination reaction is carried out on phenylacetic acid, usually using the bromination solution as the bromine source to generate phenanthrene.

Safety Information:
-process in a well-ventilated place to avoid inhaling smoke or steam.
-When in use should wear eye protection and gloves, to avoid direct contact with the skin.
-Avoid contact with strong oxidants to avoid dangerous reactions.
-Waste should be disposed of in accordance with local regulations.

Please note that the above information is for reference only. Please consult a professional and follow safe operating procedures before performing any chemical experiments or operations.

Last Update：2024-04-09 15:17:59