2-羟基-4-三氟甲基-5-嘧啶甲酸甲酯(带1分子结晶水)

2-羟基-4-三氟甲基-5-嘧啶甲酸甲酯(带1分子结晶水) - Names and Identifiers

Name	Methyl 2-oxo-4-(trifluoromethyl)-1,2-dihydro-5-pyrimidinecarboxylate
Synonyms	METHYL 2-HYDROXY-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Methyl 2-oxo-4-(trifluoromethyl)-1,2-dihydro-5-pyrimidinecarboxylate 1,2-dihydro-2-oxo-4-(trifluoromethyl)- 5-Pyrimidinecarboxylic acid methyl ester 5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-(trifluoromethyl)-, methyl ester
CAS	886212-78-8
InChI	InChI=1S/C7H5F3N2O3/c1-15-5(13)3-2-11-6(14)12-4(3)7(8,9)10/h2H,1H3,(H,11,12,14)

2-羟基-4-三氟甲基-5-嘧啶甲酸甲酯(带1分子结晶水) - Physico-chemical Properties

Molecular Formula	C7H5F3N2O3
Molar Mass	222.12
Melting Point	208-210℃
Storage Condition	2-8°C

2-羟基-4-三氟甲基-5-嘧啶甲酸甲酯(带1分子结晶水) - Introduction

Methyl 2-oxo-4-(trifluoromethyl)-1 is an organic compound with the chemical formula C7H5F3N2O3.

Nature:
-Appearance: Colorless crystalline solid
-Melting Point: 78-81°C
-Boiling point: 250°C (decomposition)
-Density: 1.661g/cm³
-Solubility: Soluble in organic solvents

Use:
Methyl 2-oxo-4-(trifluoromethyl)-1, commonly used as an intermediate for insecticides in the agricultural field. It can be used to synthesize various insecticides, such as acaricides, insect repellents, etc.

Preparation Method:
Methyl 2-oxo-4-(trifluoromethyl)-1, the synthesis methods of methylene are mainly as follows:
-Reaction of 2-chloro-4-trifluoromethyl-5-pyrimidinecarboxylic acid methyl ester with hydrazine hydrate to obtain the product.
-React 5-methyl formate with two oxidants (Dess-Martin oxidant and sodium iodate) to obtain Methyl 2-oxo-4-(trifluoromethyl)-1.

Safety Information:
Methyl 2-oxo-4-(trifluoromethyl)-1, should be stored and used correctly, avoid contact with skin, eyes or respiratory tract. Appropriate protective equipment such as chemical goggles, gloves and protective clothing should be worn during operation. In case of accidental contact or inhalation, rinse immediately with water and seek medical help. At the same time, please comply with the relevant regulations and operating procedures.

Last Update：2024-04-10 22:29:15