2-溴-5-氯烟酸
2-Bromo-5-chloronicotinic acid
CAS: 65550-79-0
Molecular Formula: C6H3BrClNO2
2-溴-5-氯烟酸 - Names and Identifiers
| Name | 2-Bromo-5-chloronicotinic acid |
| Synonyms | 2-Bromo-5-chloronicotinic acid 2-broMo-5-chloropyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 2-broMo-5-chloro- tert-butyl 3-allyl-3-hydroxyazetidine-106-carboxylate |
| CAS | 65550-79-0 |
| InChI | InChI=1/C6H3BrClNO2/c7-5-4(6(10)11)1-3(8)2-9-5/h1-2H,(H,10,11) |
2-溴-5-氯烟酸 - Physico-chemical Properties
| Molecular Formula | C6H3BrClNO2 |
| Molar Mass | 236.45 |
| Density | 1.917±0.06 g/cm3(Predicted) |
| Boling Point | 343.1±42.0 °C(Predicted) |
| pKa | 1.75±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.629 |
2-溴-5-氯烟酸 - Introduction
2-Bromo-5-choronicotinic acid is an organic compound with the chemical formula C6H3BrClNO2. The following is a description of the nature, use, method and safety information:
Nature:
-Appearance: Usually a white crystalline solid.
-Melting point: about 135-140°C.
-Solubility: Soluble in water and some organic solvents, such as chloroform and ethanol.
-Chemical properties: 2-Bromo-5-chloronicotinic acid is an aromatic carboxylic acid with acidity and reactivity.
Use:
-Chemical intermediate: 2-Bromo-5-chloronicotinic acid can be used as an intermediate in organic synthesis for the synthesis of other compounds.
-Pesticide: It can be used as a raw material for pesticides or insecticides.
Preparation Method:
The synthesis of 2-Bromo-5-chloronicotinic acid is usually carried out by the following steps:
1.2-chloro -4-nitro pyridine and cuprous bromide are reacted to obtain 2-bromo -4-nitro pyridine.
2. 2-bromo-4-nitropyridine reacts with ammonia to generate 2-bromopyridine.
3. 2-Bromo-5-chloronicotinic acid is obtained by reacting 2-bromopyridine with sodium hypochlorite.
Safety Information:
-2-Bromo-5-choronicotinic acid has low toxicity, but it should still be operated in accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate protective equipment when using.
-In the process of operation to properly dispose of waste and solution, to avoid pollution to the environment.
-Storage should be sealed and kept away from fire and oxidizing agents.
Nature:
-Appearance: Usually a white crystalline solid.
-Melting point: about 135-140°C.
-Solubility: Soluble in water and some organic solvents, such as chloroform and ethanol.
-Chemical properties: 2-Bromo-5-chloronicotinic acid is an aromatic carboxylic acid with acidity and reactivity.
Use:
-Chemical intermediate: 2-Bromo-5-chloronicotinic acid can be used as an intermediate in organic synthesis for the synthesis of other compounds.
-Pesticide: It can be used as a raw material for pesticides or insecticides.
Preparation Method:
The synthesis of 2-Bromo-5-chloronicotinic acid is usually carried out by the following steps:
1.2-chloro -4-nitro pyridine and cuprous bromide are reacted to obtain 2-bromo -4-nitro pyridine.
2. 2-bromo-4-nitropyridine reacts with ammonia to generate 2-bromopyridine.
3. 2-Bromo-5-chloronicotinic acid is obtained by reacting 2-bromopyridine with sodium hypochlorite.
Safety Information:
-2-Bromo-5-choronicotinic acid has low toxicity, but it should still be operated in accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate protective equipment when using.
-In the process of operation to properly dispose of waste and solution, to avoid pollution to the environment.
-Storage should be sealed and kept away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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View History
2-溴-5-氯烟酸
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(Cyanomethyl)diethoxyphosphine oxide
(E)-4-氨基丁-2-烯酸甲酯盐酸盐
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochlorid...
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FERRISPEC(TM) GC
PAR-2 (6-1) AMIDE (MOUSE, RAT)
2-甲基咪唑并[1,2-A]吡啶-7-醇盐酸盐
TRANS-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐
2-氨基-5-[(4-氯苯基)氨基甲酰]-4-甲基-噻吩-3-羧酸甲酯