2-氯-6-三氟甲基-吡啶-4-胺

2-氯-6-三氟甲基-吡啶-4-胺 - Names and Identifiers

Name	2-chloro-6-(trifluoromethyl)pyridin-4-amine
Synonyms	149437 T6NJ BXFFF DZ FG 2-Chloeo-4-amino-6-trifluoromethylpyridine 2-Chloro-6-(trifluoromethyl)-4-pyridinamine 2-Chloro-6-(trifluoroMethyl)pyridin-4-aMine 2-chloro-6-(trifluoromethyl)pyridin-4-amine 2-chloro-6-(trifluoromethyl)-4-pyridinamine 2-Chloro-6-trifluoroMethyl-pyridin-4-ylaMine 4-Amino-2-chloro-6-(trifluoromethyl)pyridine 2-Chloro-4-amine-6-(trifluoromethyl)pyridine 2-Chloro-4-amino-6-(trifluoromethyl)pyridine 4-Pyridinamine, 2-chloro-6-(trifluoromethyl)-
CAS	34486-22-1
InChI	InChI=1/C6H4ClF3N2/c7-5-2-3(11)1-4(12-5)6(8,9)10/h1-2H,(H2,11,12)

2-氯-6-三氟甲基-吡啶-4-胺 - Physico-chemical Properties

Molecular Formula	C6H4ClF3N2
Molar Mass	196.56
Density	1.507
Boling Point	261℃
Flash Point	112℃
Vapor Presure	0.0118mmHg at 25°C
pKa	0.30±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.501

2-氯-6-三氟甲基-吡啶-4-胺 - Introduction

2-choro-6-(trifluoromethyl)pyridin-4-amine is an organic compound with the chemical formula C6H3ClF3N. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: colorless crystal
-Melting point: 95-98°C
-Boiling point: 220-225°C
-Density: 1.59g/cm³
-Soluble: Soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane

Use:
-2-choro-6-(trifluoromethyl)pyridin-4-amine is commonly used as an intermediate in organic synthesis and can be used to synthesize various nitrogen-containing compounds.
-It can be used to prepare pesticides, medicines and functional materials.

Preparation Method:
- 2-chloro-6-(trifluoromethyl)pyridin-4-amine can be obtained by the reaction of pyridine and trifluoromethyl chloride in the presence of hydrogen chloride. Pyridine is first dissolved in methanol or isopropanol, then trifluoromethyl chloride and hydrogen chloride are added, and the target product is obtained by high temperature reaction. After completion of the reaction, separation and purification are performed by crystallization or column chromatography.

Safety Information:
-2-choro-6-(trifluoromethyl)pyridin-4-amine is less toxic to humans under general conditions.
-Wear appropriate protective equipment such as gloves, goggles and overalls during operation.
-Avoid direct contact with skin and eyes, and ensure that the laboratory is well ventilated.
-Please follow the correct handling and storage methods to avoid contact with incompatible chemicals.
-Please strictly abide by relevant safety operation procedures during use.

Last Update：2024-04-09 02:00:45