2-氟-3-吡咯烷基甲基苯基硼酸频哪醇酯

2-氟-3-吡咯烷基甲基苯基硼酸频哪醇酯 - Names and Identifiers

Name	1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine
Synonyms	2-Fluoro-3-pyrrolidinomethylphenylboronic acid, pinacol ester 1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine Pyrrolidine, 1-[[2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-
CAS	1256360-38-9

2-氟-3-吡咯烷基甲基苯基硼酸频哪醇酯 - Physico-chemical Properties

Molecular Formula	C17H25BFNO2
Molar Mass	305.2
Storage Condition	Sealed in dry,2-8°C
Sensitive	IRRITANT
MDL	MFCD17214292

2-氟-3-吡咯烷基甲基苯基硼酸频哪醇酯 - Introduction

1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine is an organic compound. The following is an introduction to its nature, use, formulation and safety information:

1. nature:
-Appearance: 1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine is a colorless to pale yellow liquid.
-Solubility: It is soluble in common organic solvents such as dimethylformamide (DMF), dichloromethane and methanol.

2. use:
- 1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine can be used as an intermediate in the synthesis of organic compounds for drug synthesis, pesticide synthesis and other organic synthesis reactions.

3. preparation method:
-A method for the synthesis of 1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine is carried out by the following steps:
1) Reaction: 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde was reacted with pyrrolidine.
2) Extraction: The reaction mixture is extracted by a suitable solvent.
3) Separation and purification: Appropriate separation and purification steps are performed, for example, using column chromatography or freeze crystallization.

4. Safety Information:
Specific toxicity and risk data for the -1-(2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine may be limited. Use appropriate laboratory safety measures, such as wearing personal protective equipment (such as laboratory gloves and goggles), operating in a well-ventilated laboratory environment, and strictly following relevant hazardous substance handling and storage regulations.

Last Update：2024-04-09 02:00:58