2,4-二羟基吡啶
2,4-Dihydroxypyridine
CAS: 626-03-9;84719-31-3
Molecular Formula: C5H5NO2
2,4-二羟基吡啶 - Names and Identifiers
| Name | 2,4-Dihydroxypyridine |
| Synonyms | NSC 37839 NSC 119859 3-Deazauracil 2,4-Pyridinediol Pyridine-2,4-diol 4-Hydroxy-2-pyridone 2,4-Dihydroxypyridine 2(1H)-Pyridone, 4-hydroxy. 2-hydroxypyridin-4(1H)-one 2-Hydroxy-1H-pyridin-4-one 2-hydroxy-3-nitropyridin-4(1H)-one 3-Deazauracil, 4-Hydroxy-2-pyridone, 2,4-PYridinediol 2,4-Pyridinediol, 3-Deazauracil, 4-Hydroxy-2-pyridone |
| CAS | 626-03-9 84719-31-3 |
| EINECS | 210-924-8 |
| InChI | InChI=1/C5H4N2O4/c8-3-1-2-6-5(9)4(3)7(10)11/h1-2H,(H2,6,8,9) |
2,4-二羟基吡啶 - Physico-chemical Properties
| Molecular Formula | C5H5NO2 |
| Molar Mass | 111.1 |
| Density | 1.3113 (rough estimate) |
| Melting Point | 272-276 °C (lit.) |
| Boling Point | 208.19°C (rough estimate) |
| Flash Point | 110.6°C |
| Water Solubility | 6.211g/L(20 ºC) |
| Solubility | DMSO, Methanol |
| Vapor Presure | 0.00192mmHg at 25°C |
| Appearance | White crystal |
| Color | light yellow |
| BRN | 108533 |
| pKa | pK1:1.37(+1);pK2:6.45(0);pK3:13(+1) (20°C) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.4260 (estimate) |
| MDL | MFCD00006273 |
2,4-二羟基吡啶 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| RTECS | UV1146800 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
2,4-二羟基吡啶 - Reference Information
| Introduction | 2, 4-dihydroxypyridine (Pyridine-2,4-diol) is a common intermediate in organic synthesis, the appearance was pale yellow powder at normal temperature and pressure. |
| Use | 2, 4-dihydroxypyridine as a common intermediate in organic synthesis, the main purpose is to use it as a molecular skeleton for structural modification and synthesis of drug molecules. The hydroxyl group on the molecular structure has a certain acidity, which can be easily made into alkyl ether to protect it, it provides a guarantee for the subsequent conversion of the amide bond. 2, 4-dihydroxypyridine may also be involved in the synthesis of nitrogen-containing heterocyclic ligands as a modified pyridine ring. |
Last Update：2024-04-09 20:02:46
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View History
2,4-二羟基吡啶
TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE)
2-[4-氯-5-环丙基-3-(二氟甲基)吡唑-1-基]乙酸
3-硝基-4-氯-5-氨磺酰基苯甲酸
2-氯-吡啶-4-硼酸频哪醇酯2-氯-4-吡啶硼酸频呐醇酯
[(二甲基亚甲硅烷基)双[(1,2,3,3A,7A-Η)-2-甲基-4-苯基-1H-茚-1-亚基]]二甲基锆
[3-[[2-氨基-5-羟基-6-[(2-羟基-5-硝基-3-磺基苯基)偶氮]-7-磺基-1-萘基]偶氮]-2-羟基-5-磺基苯甲酸根(6-)]铬酸氢二钠
1-溴-1-丙烯(顺反异构体混合物)
CBZ-L-缬氨醇
(S)-2-氨基-3-环戊基-N-环丙基丙酰胺
TETRAMETHYLENEBIS(DIPHENYLPHOSPHINE)
2-[4-氯-5-环丙基-3-(二氟甲基)吡唑-1-基]乙酸
3-硝基-4-氯-5-氨磺酰基苯甲酸
2-氯-吡啶-4-硼酸频哪醇酯2-氯-4-吡啶硼酸频呐醇酯
[(二甲基亚甲硅烷基)双[(1,2,3,3A,7A-Η)-2-甲基-4-苯基-1H-茚-1-亚基]]二甲基锆
[3-[[2-氨基-5-羟基-6-[(2-羟基-5-硝基-3-磺基苯基)偶氮]-7-磺基-1-萘基]偶氮]-2-羟基-5-磺基苯甲酸根(6-)]铬酸氢二钠
1-溴-1-丙烯(顺反异构体混合物)
CBZ-L-缬氨醇
(S)-2-氨基-3-环戊基-N-环丙基丙酰胺