2,3-difluorobenzylamine - Names and Identifiers
Name | 2,3-difluorobenzylamine
|
Synonyms | RARECHEM AL BW 0288 Difluorobenzylamine1 2,3-Difluorobenzyamine 2,3-difluorobenzylamine 2,3-DIFLUOROBENZYLAMINE 2,3-Difluorobenzylamine (2,3-Difluorophenyl)methanamine 2,3-difluoro-benzenemethanamine (2,3-difluorophenyl)methanaminium 1-(2,3-difluorophenyl)methanamine
|
CAS | 72235-51-9
|
InChI | InChI=1/C7H7F2N/c8-6-3-1-2-5(4-10)7(6)9/h1-3H,4,10H2/p+1 |
2,3-difluorobenzylamine - Physico-chemical Properties
Molecular Formula | C7H7F2N
|
Molar Mass | 143.13 |
Density | 1.223 g/mL at 25 °C (lit.) |
Boling Point | 65 °C/4 mmHg (lit.) |
Flash Point | 171°F |
Vapor Presure | 0.981mmHg at 25°C |
Appearance | Liquid |
Color | Clear colorless to pale yellow |
pKa | 8.38±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Sensitive | Air Sensitive |
Refractive Index | n20/D 1.495(lit.) |
2,3-difluorobenzylamine - Risk and Safety
Hazard Symbols | C - Corrosive
|
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 2735 8/PG 3 |
WGK Germany | 3 |
HS Code | 29214990 |
Hazard Note | Corrosive/Air Sensitive |
Hazard Class | 8 |
Packing Group | III |
2,3-difluorobenzylamine - Introduction
2,3-difluorobenzylamine is an organic compound with the chemical formula C7H7F2N. It is a colorless to yellow liquid with a pungent odor. The following is a description of the nature, use, preparation and safety information of 2,3-difluorobenzylamine:
Nature:
-Appearance: Colorless to yellow liquid
-Solubility: Soluble in organic solvents, slightly soluble in water
-Melting point:-31 ℃
-Boiling point: 210-212 ℃
-relative density: 1.196(20 ℃)
-Molecular weight: 137.14g/mol
-Stability: Stable, but avoid contact with oxidants, strong acids, and strong bases
Use:
- 2,3-difluorobenzylamine is commonly used as an intermediate and reagent in organic synthesis
-It can be used to synthesize fluorine-containing organic compounds, such as fluorinated aryl compounds, etc.
-Can be used as a raw material or intermediate in the drug synthesis process
Preparation Method:
- 2,3-difluorobenzylamine can be prepared by the reaction of 2-fluorophenylacetic acid and ammonia. First, 2-fluorophenylacetic acid is reacted with an excess of ammonia in an appropriate solvent, followed by purification by distillation and crystallization to obtain the target product.
Safety Information:
- 2,3-difluorobenzylamine is irritating and should be avoided from skin and eye contact
-Pay attention to good ventilation during use and avoid inhaling its steam
-Avoid contact with oxidants, strong acids, strong bases and other chemicals
-When storing and using, it should be stored in a closed container, away from fire and high temperature environment
-When preparing and handling 2,3-difluorobenzylamine, follow the laboratory safety procedures
Last Update:2024-04-09 21:01:54