1H-indazol-7-ol - Names and Identifiers
1H-indazol-7-ol - Physico-chemical Properties
Molecular Formula | C7H6N2O
|
Molar Mass | 134.14 |
Density | 1.434±0.06 g/cm3(Predicted) |
Melting Point | 179 °C |
Boling Point | 366.5±15.0 °C(Predicted) |
Flash Point | 175.464°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 9.23±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.76 |
1H-indazol-7-ol - Introduction
1H-indazol-7-ol, also known as 1H-indazol-7-ol, is an organic compound. Its chemical structure contains an indazole ring and a hydroxyl group. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1H-indazol-7-ol is a white to pale yellow solid.
-Melting point: about 183-187 degrees Celsius.
-Solubility: Soluble in common organic solvents.
Use:
1H-indazol-7-ol has certain uses in the field of medicine and chemistry.
-Pharmaceutical field: It can be used as a pharmaceutical intermediate for the synthesis of various pharmaceutical compounds. Specifically, it can be used to develop anti-inflammatory, anti-tumor, antibacterial, antiviral and other drugs.
-Chemical field: 1H-indazol-7-ol can be used as an alkaline reactant, reagent or catalyst in organic synthesis reactions. It is often used in organic synthesis to construct heterocyclic structures such as indazole, indazoline and indole.
Preparation Method:
The preparation methods of 1H-indazol-7-ol are various, and a common method is as follows:
The first generation of indazole alcohol (1H-indazol-5-ol) was reacted with primary amine under alkaline conditions to give 1H-indazol-7-ol.
Safety Information:
The specific safety information of 1H-indazol-7-ol needs to be evaluated according to the material safety data sheet provided by the specific supplier. However, as a chemical substance, the following safety precautions should be paid attention to when using:
-Avoid contact with skin, eyes and respiratory tract, and wear personal protective equipment if necessary.
-When using or operating the compound, please do it in a well-ventilated environment and avoid inhaling its vapor.
-Avoid contact with inflammables, oxidants and other substances during storage, and keep away from open flames or high temperature environments.
Last Update:2024-04-09 20:45:29