2-Cyano-3-methylindole, also known as DMI (methyl pyrazinone), is an organic compound. The following is an introduction to the nature, use, preparation and safety information of 2-cyano-3-methylindole:
Nature:
-Appearance: 2-cyano-3-methylindole is a light yellow to light brown solid.
-Solubility: Soluble in some organic solvents, such as alcohols and ketones, but almost insoluble in water.
-Melting point: about 80-90°C.
-Molecular formula: C10H8N2.
Use:
- 2-cyano-3-methylindole is an important organic synthesis intermediate, often used in the preparation of other compounds. It can participate in many reactions, for example as a nucleophile in organic synthesis, as a reagent for amphiphilic synthesis and cyclization reactions.
- DMI is also used as a fungicide and herbicide. It is commonly used in agriculture and horticulture to control the growth of weeds and pathogens.
Preparation Method:
-The preparation method of 2-cyano-3-methylindole is more complicated and usually requires more steps. A common method of preparation is the reaction of methylpyrazinone with sodium cyanide followed by acidification using concentrated hydrochloric acid.
Safety Information:
-2-cyano-3-methylindole may be harmful to the human body and the environment, so it is necessary to comply with relevant safety procedures when using it.
-It may be irritating to the eyes and skin, and may have toxic effects on the central nervous system.
-Wear appropriate personal protective equipment such as chemical gloves and goggles during operation.
-During storage and handling, avoid contact with strong oxidants to avoid dangerous reactions.
-If you accidentally expose or swallow the compound, you should seek medical attention immediately and provide relevant information to your doctor.