Name | sodium 2-mercaptoethanesulfonate |
Synonyms | Mesna MESNA MESNEX mesnaum COENZYME M MESNA SODIUM SALT 2-mercaptoethanesulfonic sodium 2-mercaptoethanesulfonate sodium 2-sulfanylethanesulfonate MERCAPTOETHANESULFONIC ACID SODIUM SALT 2-Mercaptoethanesulphonicacid,sodiumsalt 2-Mercaptoethanesulfonic acid sodium salt 2-mercaptoethanesulfonicacidmonosodiumsalt |
CAS | 19767-45-4 |
EINECS | 243-285-9 |
InChI | InChI=1/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5) |
Molecular Formula | C2H5NaO3S2 |
Molar Mass | 164.18 |
Melting Point | >240°C dec. |
Water Solubility | Soluble in water. Also soluble in methanol, DMSO (33 mg/ml) and ethanol (<1 mg/ml). |
Solubility | 200 mg plus 4.0 mL, H2O |
Appearance | White powder |
Color | White to Off-White |
Merck | 14,5909 |
BRN | 3657828 |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
MDL | MFCD00007535 |
Use | Respiratory system medication |
In vitro study | Mesna (1-1000 μM) reduces H 2 O 2 , HOCl and OH• concentrations in a dose-dependent manner, with an IC 50 of 32, 21, and 305 μM, respectively in cell-free experiments. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 2 |
RTECS | KI7968000 |
HS Code | 2930 90 98 |
Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 1887, 2048, 2098, 1683 i.v.; 2005, 2098, 1529, 1251 i.p.; 6102, >7200, 4440, 4679 orally (Brock) |