194804-85-8 - Names and Identifiers
Name | 4-Amino-2,3-difluorobenzoic acid
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Synonyms | 4-Carboxy-2,3-difluoroaniline 4-Amino-2,3-Difluorobenoic Acid 4-AMINO-2,3-DIFLUOROBENOIC ACID 4-AMINO-2,3-DIFLUOROBENZOIC ACID 4-Amino-2,3-difluorobenzoic acid Benzoic acid, 4-amino-2,3-difluoro-
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CAS | 194804-85-8
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InChI | InChI=1/C7H5F2NO2/c8-5-3(7(11)12)1-2-4(10)6(5)9/h1-2H,10H2,(H,11,12) |
194804-85-8 - Physico-chemical Properties
Molecular Formula | C7H5F2NO2
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Molar Mass | 173.12 |
Density | 1.536±0.06 g/cm3(Predicted) |
Boling Point | 320.1±42.0 °C(Predicted) |
Flash Point | 147.4°C |
Vapor Presure | 0.000135mmHg at 25°C |
pKa | 3.59±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.578 |
194804-85-8 - Introduction
4-Amino-2,3-difluorobenzoic acid, also known as 2,3-difluoro-4-aminobenzoic acid, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to light yellow crystalline
-Molecular formula: C7H6F2NO2
-Molecular weight: 171.13g/mol
-Melting point: About 122 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as alcohol, ether, etc.
-Chemical Properties: 4-Amino-2,3-difluorobenzoic acid is a weak acid that can react with strong bases to generate corresponding salts.
Use:
- 4-Amino-2,3-difluorobenzoic acid is an important intermediate compound, often used in organic synthesis, especially in the field of drug synthesis.
-It can be used as a precursor of a variety of drugs, such as the intermediate of the antidepressant floxatin hydrochloride, the intermediate of the antipsychotic drug fluxipin, etc.
Method:
The preparation method of
- 4-Amino-2,3-difluorobenzoic acid is more complicated and is generally obtained by chemical synthesis. A common preparation method includes an amination reaction or a fluorination reaction of 2,3-difluorobenzoic acid.
Safety Information:
- 4-Amino-2,3-difluorobenzoic acid has a certain irritation, should avoid contact with the skin, eyes.
-During use or preparation, good ventilation measures should be taken to avoid inhaling its dust.
-During storage, keep away from ignition and oxidizing agents.
-use or storage should comply with the appropriate safety procedures, wear appropriate protective equipment. If exposed or inhaled, rinse immediately with water or receive medical treatment.
Last Update:2024-04-09 02:00:43