186347-28-4 - Names and Identifiers
186347-28-4 - Physico-chemical Properties
186347-28-4 - Introduction
1-boc-4-cyano-4-(2-methylphenyl)-piperidine is an organic compound whose chemical structure contains a Boc protecting Group, a cyano group, and a 2-methylphenyl group.
Nature:
1-boc-4-cyano-4-(2-methylphenyl)-piperidine is a solid, usually white crystalline or white powder. It has good stability at room temperature and can be exposed to the air for a long time without obvious changes. It is highly soluble in organic solvents, such as ethanol, ether and methylene chloride.
Use:
1-boc-4-cyano-4-(2-methylphenyl)-piperidine is commonly used as an intermediate in organic synthesis. Its cyano group can participate in various chemical reactions, such as nucleophilic addition, oxidation reduction, etc. The 2-methylphenyl group can be used as a reactant or as an inhibitor. A Boc protecting group can protect an amino group from attack or reaction under certain conditions.
Method:
The preparation method of 1-boc-4-cyano-4-(2-methylphenyl)-piperidine is more complicated, and it is usually carried out by multi-step reaction. One of the common synthetic methods is to first obtain 4-cyano-4-(2-methylphenyl) piperidine by the corresponding substrate reaction, this is then reacted with Boc-NH2 in the presence of dimethyl carbonate and diethyl dimethylcarbamate to give the final product.
Safety Information:
1-boc-4-cyano-4-(2-methylphenyl)-piperidine is generally less toxic under normal conditions of use. However, it is still a chemical substance and should follow regular safe handling procedures. Appropriate protective equipment such as lab gloves and goggles should be worn during operation. Avoid direct contact with skin and eyes, and avoid inhaling its dust or vapor. Please read and follow the safety data sheets of the relevant chemicals carefully before use. If exposure or inhalation occurs, seek medical attention promptly.
Last Update:2024-04-09 20:45:29