tert-butyl carbamate is an organic compound with the chemical formula C16H23N3O2. The following is a description of its nature, use, formulation and safety information:
Nature:
tert-butyl carbamate is a white to yellowish solid with a special amino protecting group Boc (tert-butoxycarbonyl). It has good solubility and can be dissolved in common organic solvents such as dichloromethane, ethanol, dimethyl sulfoxide and aminopropanol.
Use:
tert-butyl carbamate is an important intermediate commonly used in organic synthesis. It is commonly used in drug synthesis, chemical biology, catalytic reaction and Heterocyclic Synthesis and other fields. For example, it can be used to synthesize peptide compounds, amino acid derivatives, and other biologically active molecules.
Method:
The preparation of tert-butyl carbamate can usually be obtained by reacting 3-phenylpropylamine with Boc-carbonyl chloride (tert-butoxycarbonyl chloride). The specific reaction conditions can be adjusted according to the experimental requirements.
Safety Information:
When handling tert-butyl carbamate, care should be taken to comply with laboratory regular safety procedures. It may irritate the eyes, skin and respiratory system. Therefore, appropriate protective equipment such as lab gloves and goggles should be worn during operation. In addition, the compound should be stored and handled properly to avoid exposure to ignition sources and strong oxidants.