175277-67-5 - Names and Identifiers
Name | 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine
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Synonyms | 4-AMINO-2,3-DIFLUOROBENZOTRIFLUORIDE 2,3-DIFLUORO-4-(TRIFLUOROMETHYL)ANILINE 3-Amino-2,6-dichloro-4-(trifluoromethyl) 2,3-DIFLUORO-4-TRIFLUOROMETHYL-PHENYLAMINE 2,6-dichloro-4-(trifluoromethyl)pyridin-3-amine 2,6-Dichloro-4-(trifluoromethyl)-3-pyridinamine 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine 3-AMINO-2,6-DICHLORO-4-(TRIFLUOROMETHYL)PYRIDINE 3-Amino-2,6-dichloro-4-(trifluoromethyl)-pyridine 3-[2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl]propanenitrile
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CAS | 175277-67-5
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InChI | InChI=1/C9H7F3N2O/c10-9(11,12)7-2-3-8(15)14(6-7)5-1-4-13/h2-3,6H,1,5H2 |
175277-67-5 - Physico-chemical Properties
Molecular Formula | C6H3Cl2F3N2
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Molar Mass | 231 |
Density | 1.622 |
Melting Point | 45-48°C |
Boling Point | 280℃ |
Flash Point | 123℃ |
Vapor Presure | 0.000177mmHg at 25°C |
pKa | -2.23±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.472 |
175277-67-5 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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Hazard Class | IRRITANT |
175277-67-5 - Introduction
3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine is an organic compound with the chemical formula C8H5Cl2F3N, abbreviated as ADTN. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine is a white or off-white solid.
-Solubility: It can be dissolved in some organic solvents, such as dimethylformamide, dichloromethane and dimethyl sulfoxide, but its solubility in water is low.
-Melting point: The melting point of the compound is about 119-121°C.
-Stability: It is relatively stable under regular experimental conditions.
Use:
- 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine is commonly used as a chemical reagent in organic synthesis.
-It can be used as a raw material for synthesis, catalysis and flame retardants.
-The compound also has some applications in the field of medicine.
Method:
The preparation method of 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine includes the following steps:
1.4-amino -3-chlorine -5-(trifluoromethyl) pyridine and nucleophilic reagent (such as base) reaction, generate the corresponding ammonia salt.
2. The ammonia salt is reacted with an acid to generate 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine.
Safety Information:
- 3-amino-2,6-dichloro-4-(trifluoromethyl)pyridine has certain toxicity and can cause irritation and damage to the human body. Use should follow the safe operation specification, and take the necessary protective measures.
-Avoid inhalation, contact with skin and eyes. Use should wear protective gloves, protective glasses and protective masks.
-During use or storage, care should be taken to avoid contact with oxidants and other substances to prevent dangerous reactions.
-Do not release this compound into the environment, and comply with relevant environmental protection regulations. The relevant regulations shall be strictly observed in the disposal of waste. For specific safety instructions, please refer to the relevant chemical Safety Data Sheet (MSDS).
Last Update:2024-04-09 02:00:43