171178-46-4 - Names and Identifiers
171178-46-4 - Physico-chemical Properties
Molecular Formula | C11H13ClN2O4
|
Molar Mass | 272.68 |
Density | 1.390±0.06 g/cm3(Predicted) |
Boling Point | 420.6±45.0 °C(Predicted) |
pKa | 2.52±0.36(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Irritant |
MDL | MFCD09258838 |
171178-46-4 - Risk and Safety
Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
|
HS Code | 29333990 |
Hazard Class | IRRITANT |
171178-46-4 - Introduction
4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimethyllethoxy) carbonyl]amino]-(pyridinecarboxylic acid) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimenthylethoxy) carbonyl]amino]-is a white to yellowish solid. It has a chemical structure with a relative molecular mass of 280.711g/mol and a molecular formula of C13H14ClNO4. It has a melting point of about 185-190 ° C. And is soluble in some organic solvents such as methylene chloride and methanol.
Use:
4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimenthylethoxy) carbonyl]amino]-is a commonly used intermediate compound, which is widely used in the field of organic synthesis. It can be used as a raw material for the synthesis of anticancer drugs, pesticides, drug candidate compounds, etc. In addition, it can also be used for the Study of ligand design and organic reactions.
Method:
Usually, 4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimenthylethoxy) the synthesis of carbonyl]amino]-can be achieved by reacting 5-amino-2-chloropyridine-4-carboxylic acid with BOC-NH2(t-butoxycarbonylammonia). The reaction generally takes place in a suitable solvent, such as dichloromethane or acetonitrile, at ambient temperature.
Safety Information:
4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimenthylethoxy) carbonyl]amino]-relatively safe for the human body under general operating conditions. However, like most chemicals, it should be handled with caution. Follow appropriate laboratory safety procedures and wear appropriate protective equipment when using or handling 4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimenthylethoxy) carbonyl]amino], such as laboratory gloves and goggles, to avoid any direct contact or other dangerous situation. In addition, it should be stored in a dry, well-ventilated place, away from fire and flammable materials. It is best to store in a special chemical storage cabinet and keep it away from children and pets. When handling this compound, care should be taken to follow relevant regulations and safe handling guidelines.
Last Update:2024-04-09 21:32:38